353497-28-6

Basic information

• Product Name: N,N-dimethyl-2-(2-toluidino)benzamide
• Synonyms: N,N-dimethyl-2-(2-toluidino)benzamide
• CAS NO: 353497-28-6
• Molecular Weight: 254.332
• Mol File: 353497-28-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N-dimethyl-2-(2-toluidino)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl-2-(2-toluidino)benzamide(353497-28-6)
• EPA Substance Registry System: N,N-dimethyl-2-(2-toluidino)benzamide(353497-28-6)

Safety Data

• Hazardous Substances Data: 353497-28-6(Hazardous Substances Data)

Upstream product

• 54616-47-6 o-bromo-N,N'-dimethylbenzamide 
• 95-53-4 o-toluidine 

Downstream Products

• 332081-65-9 N,N-dimethyl-2-[o-tolyl-(3,4,5-trimethoxy-benzyl)-amino]-benzamide 
• 1093239-41-8 N,N-dimethyl-2-(2,N-dimethylanilino)benzamide 
• 4698-11-7 10-methoxy-5H-dibenzo[b,f]azepine 
• 21737-58-6 10,11-dihydro-5H-dibenzo[b,f]azepin-10-one 
• 28721-07-5 oxcarbazepine 
• 332081-66-0 2-(allyl-o-tolyl-amino)-N,N-dimethyl-benzamide 

Relevant articles and documents

New synthesis of oxcarbazepine via remote metalation of protected N-o-tolyl-anthranilamide derivatives

Benzyl and allyl protected N-o-tolyl-anthranilamides were efficiently prepared by Buchwald-Hartwig C-N cross coupling reactions, followed by protection of the amino group. Under directed remote metalation conditions, protected dibenzoazepinones were obtained in good yields. Deprotection of the amine and conversion to an urea furnished a new and efficient synthesis of the antiepileptic drug Trileptal.