35359-22-9 Usage
Derivative of quinoline
A heterocyclic aromatic organic compound 1-methyl[1,2,4]triazolo[4,3-a]quinoline is derived from quinoline, which is a naturally occurring heterocyclic compound with aromatic properties.
Pharmaceutical and research applications
Potential medicinal properties This compound is widely used in the pharmaceutical industry and research settings due to its potential health benefits and therapeutic uses.
Antimicrobial and antitumor potential
Studied for its ability to fight infections and prevent the growth of cancer cells 1-methyl[1,2,4]triazolo[4,3-a]quinoline has been researched for its potential as an antimicrobial agent, capable of combating various infections, and as an antitumor agent, which may help prevent the growth and spread of cancer cells.
Drug development
Contribution to the creation of new medications The compound has been investigated for its potential use in the development of new drugs, thanks to its unique structure and properties.
Treatment of neurological disorders
Potential use in addressing neurological conditions 1-methyl[1,2,4]triazolo[4,3-a]quinoline has been explored as a possible treatment for neurological disorders, due to its potential impact on the nervous system.
Precursor in organic synthesis
用作其他化合物合成的起始物质 This compound serves as a starting material in organic synthesis, which means it can be used to create other compounds with various applications in science and medicine.
Unique structure and properties
Valuable for scientific and medical research The distinctive structure and properties of 1-methyl[1,2,4]triazolo[4,3-a]quinoline make it an important compound for a wide range of scientific and medical research purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 35359-22-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,3,5 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 35359-22:
(7*3)+(6*5)+(5*3)+(4*5)+(3*9)+(2*2)+(1*2)=119
119 % 10 = 9
So 35359-22-9 is a valid CAS Registry Number.
35359-22-9Relevant articles and documents
Nitroalkanes as electrophiles: Synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity
Aksenov, Alexander V.,Aksenov, Dmitrii A.,Aksenov, Nicolai A.,Arutiunov, Nikolai A.,Du, Liqin,Kirilov, Nikita K.,Kornienko, Alexander,Maslivetc, Vladimir,Rubin, Michael,Zhao, Zhenze
, p. 6651 - 6664 (2020/09/21)
We discovered a reaction of nitroalkanes with 2-hydrazinylquinolines, 2-hydrazinylpyridines and bis-2,4-dihydrazinylpyrimidines in polyphosphoric acid (PPA) affording 1,2,4-triazolo[4,3-a]quinolines, 1,2,4-triazolo[4,3-a]pyridines and bis[1,2,4]triazolo[4,3-a:4′,3′-c]pyrimidines, respectively. The reaction expands the scope of heterocyclic annulations involving phosphorylated nitronates, believed to be the electrophilic intermediates formed from nitroalkanes in PPA. Several of the synthesized triazoles showed promising anticancer activity by inducing differentiation in neuroblastoma cancer cells. Due to the urgent need for novel differentiation agents for neuroblastoma therapy, this finding warrants further evaluation of this class of compounds against neuroblastoma.
STUDIES ON THIOAMIDES AND THEIR DERIVATIVES. PART II. REACTION OF QUATERNARY SALTS OF N,N-DISUBSTITUTED THIOAMIDES WITH 2-HYDRAZINOQUINOLINE
Santus, Maria
, p. 661 - 671 (2007/10/02)
In reactions of methyliodides of N,N-disubstituted thioamides with 2-hydrazinoquinoline a series of new compounds have been obtained: iodohydrides, derivatives of 1-α-morpholinobenzylidene-2-quinolinohydrazine and of 1-α-piperidinobenzylidene-2-quinolinohydrazine.The compounds obtained, when transformed into free bases, undergo cyclization to derivatives of s-triazolo(4,3-a)quinoline system under the effect of glacial acetic acid.All these compounds have been characterized by means of UV and IR spectra.
