354-76-7 Usage
Description
PENTAFLUOROPROPIONAMIDE, also known as 2,2,3,3,3-Pentafluoropropionamide, is an organic compound that serves as a valuable intermediate in the synthesis of various chemical, pharmaceutical, and organic products. Its unique structure, featuring a pentafluoropropionyl group, endows it with specific properties that make it suitable for a range of applications.
Uses
Used in Chemical Industry:
PENTAFLUOROPROPIONAMIDE is used as a chemical intermediate for the synthesis of various compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. Its unique pentafluoropropionyl group allows for the development of novel molecules with enhanced properties and improved performance.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, PENTAFLUOROPROPIONAMIDE is used as a key intermediate in the production of various drug candidates. Its incorporation into drug molecules can lead to improved pharmacokinetics, increased potency, and better selectivity, making it a valuable component in the development of new therapeutic agents.
Used in Organic Synthesis:
PENTAFLUOROPROPIONAMIDE is utilized as a versatile building block in organic synthesis, enabling the creation of a wide range of organic compounds with diverse applications. Its reactivity and stability make it an attractive choice for the synthesis of complex organic molecules.
Overall, PENTAFLUOROPROPIONAMIDE is a multifaceted intermediate with applications across various industries, including chemical, pharmaceutical, and organic synthesis, due to its unique properties and potential for creating innovative products.
Check Digit Verification of cas no
The CAS Registry Mumber 354-76-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,5 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 354-76:
(5*3)+(4*5)+(3*4)+(2*7)+(1*6)=67
67 % 10 = 7
So 354-76-7 is a valid CAS Registry Number.
InChI:InChI=1/C3H2F5NO/c4-2(5,1(9)10)3(6,7)8/h(H2,9,10)
354-76-7Relevant articles and documents
-
Hauptschein,M.,Braid,M.
, p. 2500 - 2505 (1961)
-
-
Husted,Ahlbrecht
, p. 1605,1607 (1953)
-
FLUOROALKYL-CONTAINING β,β'-TRICARBONYL COMPOUNDS: TAUTOMERISM AND REACTION WITH N-NUCLEOPHILES
Krokhalev, V. M.,Saloutin, V. I.,Romas', A. D.,Ershov, B. A.,Pashkevich, K. I.
, p. 316 - 322 (2007/10/02)
The tautomeric composition of α-polyfluoroacyl derivatives of acetylacetone and malonic ester has been established and it has been shown that with N-nucleophiles (ammonia, 1,2-ethylenediamine, o-phenylenediamine) these compounds undergo 'acid' decomposition with the elimination of the polyfluoroacyl group.With hydrazines, malonic ester derivatives react similarly but acetylacetone derivatives undergo cyclization into pyrazoles.The regiodirectivity of the interaction of fluoroalkyl-containing β,β'-tricarbonyl compounds with N-nucleophiles does not depend on their tautomeric composition and is determined by orbital control.
SYNTHESIS AND REACTIONS OF OXYGEN CONTAINING ORGANOFLUORINE COMPOUNDS. IX. REACTION OF POLYFLUOROALKYL KETONES WITH AMMONIA
Saloutina, L. V.,Zapevalov, A. Ya.,Kolenko, I. P.
, p. 2019 - 2024 (2007/10/02)
The reaction of polyfluoroalkyl ketones with ammonia at reduced temperature was studied.The products from addition of ammonia at the carbonyl group, i.e., geminal amino alkohols, were obtained.If there are chlorine and bromine atoms at the α position, the polyfluoroalkyl ketones dissociate under the influence of ammonia to carboxamides and polyhalogenoalkanes.
