354153-40-5Relevant articles and documents
Asymmetric synthesis of the four possible fagomine isomers
Takahata, Hiroki,Banba, Yasunori,Ouchi, Hidekazu,Nemoto, Hideo,Kato, Atsushi,Adachi, Isao
, p. 3603 - 3607 (2007/10/03)
The asymmetric synthesis of fagomine and its congeners 1-4 has been achieved by catalytic ring-closing metathesis (RCM). The synthesis involved the construction of the piperidene-type chiral building block 5 followed by dihydroxylation, starting from the D-serine-derived Garner aldehyde 6.