3548-71-8

Basic information

• Product Name: α-Acetamido-cinnamaldehyd
• Synonyms: α-Acetamido-cinnamaldehyd
• CAS NO: 3548-71-8
• Molecular Weight: 189.214
• Mol File: 3548-71-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: α-Acetamido-cinnamaldehyd(CAS DataBase Reference)
• NIST Chemistry Reference: α-Acetamido-cinnamaldehyd(3548-71-8)
• EPA Substance Registry System: α-Acetamido-cinnamaldehyd(3548-71-8)

Safety Data

• Hazardous Substances Data: 3548-71-8(Hazardous Substances Data)

Upstream product

• 85483-61-0 acetamido acetaldehyde diethyl acetal 
• 100-52-7 benzaldehyde 
• 3509-71-5 α-Oximino-β,β-dimethoxy-propiophenon 
• 881-90-3 4-benzylidene-2-methyl-2-oxazolin-5-one 
• 52386-78-4 N-acetyl dehydrophenylalanine methyl ester 
• 3548-72-9 N-(3-hydroxy-1-phenylprop-1-en-2-yl)acetamide 

Relevant articles and documents

Lewis Acid-Catalyzed Nucleophilic Addition of Indoles to in Situ-Generated 2-Amidoallyl Cations

We report herein the first Lewis acid-catalyzed generation of 2-amidoallyl cations through ring-opening of 4-benzylidene-2-oxazolines with Sc(OTf)3. Upon nucleophilic addition of indoles, indolylenamides were obtained with yields of 60-99% and excellent (Z)-selectivity. In addition, the novel strategy was also successfully applied to pyrroles and naphthols as -nucleophiles. A Br?nsted acid-catalyzed process using TfOH formed in situ was ruled out by control experiments.

Physical characteristics and polarographic reduction mechanism of some oxazolones

The redox potential (ΔE1/2), electron affinity (EA), ionization potential (IP), coulomb repulsion integral (J12), and electronic transition energy (ECT) of several oxazolone derivatives in DMF were computed.A linear correlation was shown to exist between ΔE1/2 and ECT.The polarographic reduction was investigated in ethanolic-Theil buffer solutions.At pH /= 7.2, two waves were obtained representing the uptake of 2- and 4-electron steps respectively.In alkaline media, a third wave appeared seemingly a result of the hydrolysis of oxazolones.The rate of hydrolysis was determined and the electrode mechanism was elucidated and confirmed via spectrophotometric and coulometric analysis. Key words: oxazolones, polarography, electrochemistry, electrode reaction, spectrophotometry, redox potential.