3553-20-6 Usage
Description
(2,5-DIOXO-HEXAHYDRO-IMIDAZO[4,5-D]-IMIDAZOL-1-YL)-ACETIC ACID, also known as thalidomide, is a synthetic derivative of glutamic acid with a complex imidazole ring structure. Initially used as a sedative and antiemetic medication, it was withdrawn from the market due to its teratogenic effects. Thalidomide has since been repurposed for the treatment of multiple myeloma and leprosy, and is being studied for its potential in managing various inflammatory and autoimmune conditions. Its mechanism of action involves inhibiting the production of tumor necrosis factor-alpha and other inflammatory cytokines, as well as modulating the immune response.
Uses
Used in Oncology:
(2,5-DIOXO-HEXAHYDRO-IMIDAZO[4,5-D]-IMIDAZOL-1-YL)-ACETIC ACID is used as an anti-cancer agent for the treatment of multiple myeloma, a malignant proliferation of plasma cells. It helps in reducing the growth and spread of cancer cells by targeting the tumor microenvironment and modulating the immune system.
Used in Dermatology:
In the treatment of leprosy, (2,5-DIOXO-HEXAHYDRO-IMIDAZO[4,5-D]-IMIDAZOL-1-YL)-ACETIC ACID is used as an immunomodulatory agent to reduce inflammation and alleviate symptoms associated with the disease. It helps in managing the immune response and decreasing the severity of skin lesions and nerve damage.
Used in Inflammatory and Autoimmune Conditions:
(2,5-DIOXO-HEXAHYDRO-IMIDAZO[4,5-D]-IMIDAZOL-1-YL)-ACETIC ACID is being studied for its potential applications in various inflammatory and autoimmune conditions. It is used as an immunomodulatory agent to regulate the immune system and reduce inflammation, which can help in managing the symptoms and progression of these conditions.
Used in Pharmaceutical Research:
In the field of pharmaceutical research, (2,5-DIOXO-HEXAHYDRO-IMIDAZO[4,5-D]-IMIDAZOL-1-YL)-ACETIC ACID serves as a valuable compound for the development of new drugs and therapies. Its unique structure and properties make it a promising candidate for the treatment of various diseases, including cancer, inflammatory disorders, and autoimmune conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 3553-20-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,5 and 3 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3553-20:
(6*3)+(5*5)+(4*5)+(3*3)+(2*2)+(1*0)=76
76 % 10 = 6
So 3553-20-6 is a valid CAS Registry Number.
3553-20-6Relevant articles and documents
New functional glycoluril derivatives
Chegaev,Kravchenko,Lebedev,Strelenko
, p. 32 - 33 (2001)
Functional glycoluril (2,4,6,8-tetraazabicyclo[3.3.0]octan-3,7-dione) derivatives containing 2-hydroxyethyl, carboxyl and amino groups were synthesised.
