35572-23-7

Basic information

• Product Name: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(1-piperidinyl)-, (E)-
• CAS NO: 35572-23-7
• Molecular Formula: C14H17NO2
• Molecular Weight: 231.294
• Mol File: 35572-23-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(1-piperidinyl)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(1-piperidinyl)-, (E)-(35572-23-7)
• EPA Substance Registry System: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(1-piperidinyl)-, (E)-(35572-23-7)

Safety Data

• Hazardous Substances Data: 35572-23-7(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 39079-62-4 chromone-3-carboxylic acid 
• 57443-89-7 (2E)-ethyl 3-oxo-2-((4-oxo-4H-chromen-3-yl)methylene)butanoate 
• 1776-08-5 (E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one 
• 491-38-3 1-benzopyran-4(4H)-one 
• 4540-33-4 piperdinium acetate 
• 118-93-4 o-hydroxyacetophenone 
• 17422-74-1 3-Formylchromone 
• 88021-75-4 3-[1,3]Dioxan-2-yl-chromen-4-one 
• 17422-79-6 2-(4-oxo-4H-1-benzopyran-3-yl)-1,3-dioxolane 
• 42059-84-7 diethyl 2-((4-oxo-4H-chromen-3-yl)methylene)malonate 
• 128402-88-0 ethyl α-cyano-β-(4-oxo-4H-1-benzopyran-3-yl)acrylate 
• 4197-99-3 3-benzoyl-4H-chromen-4-one 
• 17422-75-2 3-acetyl-4H-chromen-4-one 

Downstream Products

• 49619-82-1 3-bromo-4H-chromen-4-one 
• 491-38-3 1-benzopyran-4(4H)-one 

Relevant articles and documents

Michael-Aldol Double Elimination Cascade to Make Pyridines: Use of Chromone for the Synthesis of Indolizines

A domino Michael-aldol double elimination route to indolizines having two different acyl groups at the C5 and C7 positions is described where chromone is employed as a two-carbon unit for the synthesis of a pyridine moiety for the first time. Various analogues were readily accessed in good yields under metal-free and eco-friendly conditions. Further manipulation of the resulting products allowed entry to novel indolizine-heterocycle adducts, which are difficult to access by other methods.

X-ray diffraction and VT-NMR studies of (E)-3-(piperidinyl)-1-(2′-hydroxyphenyl)-prop-2-en-1-one

A series of 1-aryl-3-(cyclicamino)-prop-2-en-1-one analogs was synthesized from commercial acetophenones in 2 or 3 steps. Compound 6, (E)-3-(piperidinyl)-1-(2′-hydroxyphenyl)-prop-2-en-1-one, exhibited the unique shape and intensity of the Csp2

Benzopyrans: Part XIX - Reactions of 3-Acetyl- and 3-Acetyl-2-methyl-4-oxo-4H-benzopyrans with Nitrogen Nucleophiles

3-Acetyl-4-oxo-4H-benzopyran (1a) gives with piperidine the enaminoketone (2); with phenylhydrazine a mixture of the pyrazoles (5a and 7a, R'=Ph); and with hydroxylamine the nitrile (12) and isoxazole (13a) under two different conditions.Like 1a, the chromenone (1b) also behaves as a Michael acceptor towards hydrazine and hydroxylamine to produce the pyrazoles (7b, R'=H, Ph) and isoxazole (13b), respectively.Guanidine forms the pyrimidine (17a) with 1a, but 18b with 1b.