35601-81-1

Basic information

• Product Name: isopropyl ethylcarbamate
• Synonyms: isopropyl ethylcarbamate;Ethylcarbamic acid 1-methylethyl ester
• CAS NO: 35601-81-1
• Molecular Formula: C6H13NO2
• Molecular Weight: 131.17292
• EINECS: 252-636-5
• Mol File: 35601-81-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 183.8°Cat760mmHg
• Flash Point: 65°C
• Appearance: /
• Density: 0.935g/cm³
• Vapor Pressure: 0.756mmHg at 25°C
• Refractive Index: 1.415
• CAS DataBase Reference: isopropyl ethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: isopropyl ethylcarbamate(35601-81-1)
• EPA Substance Registry System: isopropyl ethylcarbamate(35601-81-1)

Safety Data

• Hazardous Substances Data: 35601-81-1(Hazardous Substances Data)

Usage

General Description

Isopropyl ethylcarbamate, also known as diethylcarbamazine, is a chemical compound that is used as an insect repellent and as a pharmaceutical drug in the treatment of parasitic infections such as filariasis. It is a synthetic anthelmintic agent that works by paralyzing and killing the worms in the body. Isopropyl ethylcarbamate is also used in topical medications to relieve itching and as a preservative in cosmetics and personal care products. However,

InChI:InChI=1/C6H13NO2/c1-4-7-6(8)9-5(2)3/h5H,4H2,1-3H3,(H,7,8)

Upstream product

• 75-04-7 ethylamine 
• 74305-11-6 C₅H₁₀N₂O₄ 
• 67-63-0 isopropyl alcohol 
• 109-90-0 ethyl isocyanate 

Relevant articles and documents

Removal of flotation collector O-isopropyl-N-ethylthionocarbamate from wastewater

Flotation collector O-isopropyl N-ethylthionocarbamate (IPETC) is widely used for separation of sulfide ores. Its removal from water by several oxidation processes was studied. Photocatalytic oxidation with air in the presence of iron salts, utilizing solar irradiation or artificial UV-A light is very efficient. Oxidation leads through the formation of O-isopropyl N-ethylcarbamate and several other reaction intermediates to total decomposition of organic compound in the final stage in 1 day. Similar results were obtained with a Fenton type oxidation with hydrogen peroxide and iron salts. Treatment with sodium hypochlorite yields mainly O-isopropyl N-ethylcarbamate. The formation of this compound in wastewaters can be of concern, since simple alkyl carbamates are cancer suspect agents.

Nucleophilic Substitutions to Carbonic Acid Derivates. XII. Kinetics and Mechanism of the Reaction of N-Nitro-N-alkyl-urethanes with Primary Aliphatic Amines

The aminolysis of N-alkyl-N-nitrourethanes takes place, as the kinetical studies demonstrate, by means of several consecutive steps.The nucleophilic attack of the amine (first step; reaction B), as well as the proton-transfere (second step; reaction C), are quick pre-equilibres, followed by the slow, rate-determining elimination of the nitramino-group (reaction D).During the deprotonation, an intermediate with two to the nitramino-group antiperiplanar orbitals is formed, providing the necessary mesomeric assistance of the elimination.