356063-47-3

Basic information

• Product Name: (20S)-21-[[Tris(isopropyll)silyl]oxy]-20-methyl-pregn-4-en-3-one
• Synonyms: (20S)-21-[[Tris(isopropyll)silyl]oxy]-20-methyl-pregn-4-en-3-one
• CAS NO: 356063-47-3
• Molecular Formula: C₃₁H₅₄O₂Si
• Molecular Weight: 486.84476
• Mol File: 356063-47-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 529.1±19.0 °C(Predicted)
• Appearance: /
• Density: 0.97±0.1 g/cm3(Predicted)
• CAS DataBase Reference: (20S)-21-[[Tris(isopropyll)silyl]oxy]-20-methyl-pregn-4-en-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (20S)-21-[[Tris(isopropyll)silyl]oxy]-20-methyl-pregn-4-en-3-one(356063-47-3)
• EPA Substance Registry System: (20S)-21-[[Tris(isopropyll)silyl]oxy]-20-methyl-pregn-4-en-3-one(356063-47-3)

Safety Data

• Hazardous Substances Data: 356063-47-3(Hazardous Substances Data)

Usage

Chemical Properties

Brown Oil

Uses

Intermediate in the preparation of meiosis regulating medications.

Upstream product

• 13154-24-0 triisopropylsilyl chloride 
• 40736-33-2 (20S)-20-hydroxymethylpregn-4-en-3-one 
• 288-32-4 1H-imidazole 

Downstream Products

• 64284-64-6 4,4-DIMETHYL-5ALPHA-CHOLESTA-8,14,24-TRIENE-3BETA-OL 
• 242142-71-8 (3S,9S,10R,13R,14R,17R)-17-((R)-1,5-Dimethyl-hex-5-enyl)-4,4,10,13-tetramethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 
• 592536-32-8 (20S)-4,4,20-trimethyl-pregna-5,7-dien-3β,21-diol benzoate 
• 841288-42-4 (20S)-4,4-dimethyl-20-[((triisopropylsilyl)oxy)methyl]-pregna-5,7-dien-3β-ol benzoate 
• 552302-71-3 (20S)-4,4-dimethyl-20-[((toluene-4-sulfonyl)oxy)methyl]-pregna-5,7-dien-3β-ol benzoate 
• 552302-70-2 (20S)-4,4-dimethyl-20-[((triisopropylsilyl)oxy)methyl]-pregna-5-en-3β-ol benzoate 

Relevant articles and documents

Two syntheses of FF-MAS

(Matrix presented) Follicular fluid-meiosis activating sterol (FF-MAS) has been shown to be an efficient inducer of meiotic maturation. It can potentially be used for improvements of in vitro fertilization techniques. Two short synthesis of FF-MAS are pre

Steroid derivatives with an additional ring annulated to ring A and use of these derivatives for the preparation of meiosis regulating medicaments

The present invention relates to pharmaceutically active steroid derivatives with an additional ring annulated to ring A, to pharmaceutical compositions comprising and to the use of these compounds for the preparation of medicaments. More particularly it has been found that the described steroids of the invention can be used for regulating meiosis.