356086-86-7 Usage
Description
4-P-TOLYLAMINO-BUTAN-1-OL, also known as p-toluidine butanol, is an organic compound characterized by its chemical formula C11H17NO. It presents as a white to off-white crystalline solid, which is insoluble in water but readily soluble in organic solvents. This versatile intermediate is widely utilized in the synthesis of various products, including pharmaceuticals, dyes, and other organic compounds, due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
4-P-TOLYLAMINO-BUTAN-1-OL is used as a key intermediate in the synthesis of pharmaceuticals for its ability to react and form new compounds that possess therapeutic properties. Its role in drug development is crucial, as it can contribute to the creation of new medications that address various health conditions.
Used in Dye Industry:
In the dye industry, 4-P-TOLYLAMINO-BUTAN-1-OL is utilized as an intermediate for the production of dyes. Its chemical structure allows for the creation of colorants that can be used in a variety of applications, including textiles, plastics, and printing inks, due to its reactivity and ability to form stable dye molecules.
Used in Organic Synthesis:
4-P-TOLYLAMINO-BUTAN-1-OL is used as a reagent in organic synthesis, where it participates in various chemical reactions to form a range of organic compounds. Its versatility in reacting with different substances makes it a valuable component in the synthesis of specialty chemicals and materials.
Used in Chemical Product Production:
As a component in the production of chemical products, 4-P-TOLYLAMINO-BUTAN-1-OL contributes to the manufacturing process of a diverse array of chemical goods. Its inclusion in these processes is essential for achieving desired product characteristics such as color, stability, or reactivity.
While 4-P-TOLYLAMINO-BUTAN-1-OL does not present known major health hazards, it is imperative to handle this compound with care, adhering to established safety guidelines to ensure the well-being of individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 356086-86-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,6,0,8 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 356086-86:
(8*3)+(7*5)+(6*6)+(5*0)+(4*8)+(3*6)+(2*8)+(1*6)=167
167 % 10 = 7
So 356086-86-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H17NO/c1-10-4-6-11(7-5-10)12-8-2-3-9-13/h4-7,12-13H,2-3,8-9H2,1H3
356086-86-7Relevant articles and documents
A new palladium-mediated approach to 4-N-arylamino-1-butanols from peroxidic tetrahydrofuran and primary aromatic amines
Russell, Henry F.,Bremner, John B.,Bushelle-Edghill, Jennifer,Lewis, Melissa R.,Thomas, Stacey R.,Bates II, Floyd
, p. 1637 - 1639 (2007)
Reaction of primary aromatic amines with peroxidic tetrahydrofuran (THF) in the presence of hydrogen and 10% palladium on carbon catalyst results in THF ring opening to give 4-N-arylamino-1-butanols in a good yield. The reaction mechanism is believed to i
An efficient and atom-economical route to: N -aryl amino alcohols from primary amines
Xiao, Zhen,Li, Juanjuan,Yue, Qiang,Zhang, Qian,Li, Dong
, p. 34304 - 34308 (2018/10/24)
In this paper we reported a novel method for generation of N-aryl amino alcohols from N,N-disubstituted picolinamides through reduction/ring-opening reaction with NaBH4. The N,N-disubstituted picolinamides can be easily obtained from primary am
Rhodium(III)-catalyzed N-nitroso-directed C-H addition to ethyl 2-oxoacetate for cycloaddition/fragmentation synthesis of indazoles
Chen, Jinsen,Chen, Pei,Song, Chao,Zhu, Jin
supporting information, p. 14245 - 14249 (2015/02/05)
RhIII-catalyzed N-nitroso-directed C-H addition to ethyl 2-oxoacetate allows subsequent construction of indazoles, a privileged heterocycle scaffold in synthetic chemistry, through the exploitation of reactivity between the directing group and installed group. The formal [2+2] cycloaddition/fragmentation reaction pathway identified herein, a unique reactivity pattern hitherto elusive for the N-nitroso group, emphasizes the importance of forward reactivity analysis in the development of useful C-H functionalization-based synthetic tools. The synthetic utility of the protocol is demonstrated with the synthesis of a tri-cyclic-fused ring system. The diversity of covalent linkages available for the nitroso group should enable the extension of the genre of reactivity reported herein to the synthesis of other types of heterocycles.