35642-74-1Relevant articles and documents
1-Aza-1',3'-diaza-3,3'-sigmatropic rearrangements - A convenient synthesis of benzimidazole derivatives
Teresa,Carvalho,Lobo, Ana M.,Branco, Paula S.,Prabhakar, Sundaresan
, p. 3115 - 3118 (2007/10/03)
1-Aryl-2-acyl-2-cyanohydrazines undergo smooth thermal rearrangements to provide 2-aminoacylbenzimidazoles in excellent yields. A short synthesis of the highly mutagenic dietary amine, IQ, is reported.