35688-72-3

Basic information

• Product Name: 2-Cyano-3-naphthalen-2-yl-acrylic acid ethyl ester
• Synonyms: ethyl (2Z)-2-cyano-3-(naphthalen-2-yl)prop-2-enoate
• CAS NO: 35688-72-3
• Molecular Formula: C₁₆H₁₃NO₂
• Molecular Weight: 251.28
• Mol File: 35688-72-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 428.8°Cat760mmHg
• Flash Point: 211.4°C
• Appearance: /
• Density: 1.192g/cm³
• Vapor Pressure: 1.47E-07mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: 2-Cyano-3-naphthalen-2-yl-acrylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyano-3-naphthalen-2-yl-acrylic acid ethyl ester(35688-72-3)
• EPA Substance Registry System: 2-Cyano-3-naphthalen-2-yl-acrylic acid ethyl ester(35688-72-3)

Safety Data

• Hazardous Substances Data: 35688-72-3(Hazardous Substances Data)

Usage

General Description

2-Cyano-3-naphthalen-2-yl-acrylic acid ethyl ester is a chemical compound with the molecular formula C17H13NO2. It is a derivative of naphthalene and acrylic acid that is commonly used in the manufacturing of dyes and pigments. 2-Cyano-3-naphthalen-2-yl-acrylic acid ethyl ester is typically found as a colorless or yellow liquid with a faint odor and is considered to be stable under normal conditions. It is also known to be soluble in organic solvents such as ethanol and acetone. This chemical has a wide range of industrial applications, including the production of fluorescent dyes, optical brighteners, and fluorescent indicators. Additionally, it is used in the field of organic synthesis and pharmaceutical research.

InChI:InChI=1/C16H13NO2/c1-2-19-16(18)15(11-17)10-12-7-8-13-5-3-4-6-14(13)9-12/h3-10H,2H2,1H3/b15-10-

Upstream product

• 66-99-9 β-naphthaldehyde 
• 105-56-6 ethyl 2-cyanoacetate 
• 613-46-7 2-naphthalenecarbonitrile 
• 13577-85-0 N,N-dimethyl-2-naphthylcarboxamide 

Downstream Products

• 1372800-84-4 (1R,2R,6R)-triethyl 1-cyano-6-(naphthalen-2-yl)cyclohex-3-ene-1,2,3-tricarboxylate 
• 1500092-75-0 C₂₇H₂₅N₃O₆S 

Relevant articles and documents

Amides as surrogates of aldehydes for C-C bond formation: amide-based direct Knoevenagel-type condensation reaction and related reactions

Aldehydes are perhaps the most versatile compounds that enable many C-C bond forming reactions, which are not amenable for other subclasses of carbonyl compounds. We report the first use of amides as surrogates of aldehydes for C-C bond formation, namely,

Development of the First Two-Pore Domain Potassium Channel TWIK-Related K+ Channel 1-Selective Agonist Possessing in Vivo Antinociceptive Activity

The TWIK-related K+ channel, TREK-1, has recently emerged as an attractive therapeutic target for the development of a novel class of analgesic drugs, suggesting that activation of TREK-1 could result in pain inhibition. Here, we report the synthesis of a series of substituted acrylic acids (1-54) based on our previous work with caffeate esters. The analogues were evaluated for their ability to modulate TREK-1 channel by electrophysiology and for their in vivo antinociceptive activity (acetic acid-induced writhing and hot plate assays), leading to the identification of a series of novel molecules able to activate TREK-1 and displaying potent antinociceptive activity in vivo. Furyl analogue 36 is the most promising of the series.

A carboxylate-rich metalloligand and its heterometallic coordination polymers: Syntheses, structures, topologies, and heterogeneous catalysis

This work reports three heterometallic coordination polymers (HCPs), namely, [{(1′)2Zn8Na2(H2O)21}·20H2O]n (2), [{(1′)(1')Cd8(H2O)21}·32H2/