35699-44-6

Basic information

• Product Name: 2-METHYL-1-NAPHTHALDEHYDE 97
• Synonyms: 2-METHYL-1-NAPHTHALDEHYDE 97;2-Methyl-1-naphthaldehyde 97%
• CAS NO: 35699-44-6
• Molecular Formula: C₁₂H₁₀O
• Molecular Weight: 170.21
• Product Categories: Aldehydes;C10 to C21;Carbonyl Compounds;Building Blocks;C10-C12;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 35699-44-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 51-56 °C(lit.)
• Boiling Point: 316.5°Cat760mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.123g/cm³
• Vapor Pressure: 0.000409mmHg at 25°C
• Refractive Index: 1.656
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-METHYL-1-NAPHTHALDEHYDE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-1-NAPHTHALDEHYDE 97(35699-44-6)
• EPA Substance Registry System: 2-METHYL-1-NAPHTHALDEHYDE 97(35699-44-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 35699-44-6(Hazardous Substances Data)

Usage

Description

2-METHYL-1-NAPHTHALDEHYDE 97, also known as 2-Methyl-1-naphthaldehyde, is an organic compound derived from naphthalene. It is characterized by its distinct chemical structure, which features a methyl group at the 2nd position and an aldehyde group at the 1st position. 2-METHYL-1-NAPHTHALDEHYDE 97 is known for its unique chemical properties and potential applications in various industries.

Uses

Used in Chemical Synthesis:
2-METHYL-1-NAPHTHALDEHYDE 97 is used as a key intermediate in the synthesis of various organic compounds, including 2-methyl-1-naphthaldehyde tosylhydrazone. This application is particularly relevant in the pharmaceutical and chemical industries, where the compound serves as a building block for the development of new molecules with specific properties and functions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-METHYL-1-NAPHTHALDEHYDE 97 is used as a starting material for the synthesis of various drugs and drug candidates. Its unique chemical structure allows for the development of molecules with potential therapeutic applications, making it a valuable asset in drug discovery and development processes.
Used in Research and Development:
2-METHYL-1-NAPHTHALDEHYDE 97 is also utilized in research and development settings, where it can be employed to study the properties and behavior of naphthalene-based compounds. This application is particularly important in academic and industrial research laboratories, where the compound can be used to explore new chemical reactions and develop innovative synthetic methods.

InChI:InChI=1/C12H10O/c1-9-6-7-10-4-2-3-5-11(10)12(9)8-13/h2-8H,1H3

Upstream product

• 573-98-8 dimethyl-1,2 naphtalene 
• 64-19-7 acetic acid 
• 88802-84-0 1,3-dimethyl-2-(1-naphthyl)imidazolidine 
• 74-88-4 methyl iodide 
• 141-82-2 malonic acid 
• 91-57-6 2-Methylnaphthalene 
• 61172-29-0 1-bromomethyl-2-methylnaphthalene 

Downstream Products

• 573-98-8 dimethyl-1,2 naphtalene 
• 1575-96-8 2-methyl-1-naphthoic acid 
• 1308401-05-9 3-(2-methylnaphthalen-1-yl)propynoic acid benzylnaphthalen-2-ylamide 
• 1421186-99-3 1-((2-bromophenyl)ethynyl)-2-methylnaphthalene 
• 1421186-69-7 1-((2-cyclopentenylphenyl)ethynyl)-2-methylnaphthalene 
• 1421186-71-1 1-((2-cyclopentenyl-3-methoxyphenyl)ethynyl)-2-methylnaphthalene 
• 1421186-75-5 1-((2-cyclopentenyl-6-methoxyphenyl)ethynyl)-2-methylnaphthalene 
• 1421186-79-9 1-((3',5'-dimethoxybiphenyl-2-yl)ethynyl)-2-methylnaphthalene 
• 1421187-07-6 1-((2-bromo-3-methoxyphenyl)ethynyl)-2-methylnaphthalene 
• 1421187-10-1 1-((2-bromo-6-methoxyphenyl)ethynyl)-2-methylnaphthalene 

Relevant articles and documents

Facile reductive coupling of benzylic halides with ferrous oxalate dihydrate

Facile reductive coupling of benzylic halides is reported with ferrous oxalate dihydrate in DMF or HMPA under nitrogen atmosphere at 155-160°C. The coupling is proposed to proceed by two successive oxidative additions of benzylic halides to ferrous oxalate to give an intermediate organoiron complex which undergoes concerted dimerization to give the corresponding reductively coupled dimers in high yields.

Manganese(III)-Mediated Formylation of Aromatic Compounds in the Presence of Malonic Acid

The reaction of naphthlenes with malonic acid in the presence of manganese(III) acetate gives naphthalenecarbaldehydes and naphthalenecarboxylic acids.Similar reactions of anthracene, pyrene, and methoxybenzenes also yield formylated and carboxylated products.It was found that the formyl group introduced to the aromatic ring was not derived from carboxymethyl radical generated directly by the thermolysis of manganese(III) acetate, but from a dicarboxymethyl radical formed by the interaction of malonic acid and manganese(III) acetate.In addition, it was also found that the dicarboxymethyl radicals attacked the position of the highest electron density on the aromatic ring and that this formylation was effective when the ionization potential of the aromatic copound was lower than 7.8 eV.

FORMATION OF MONOALDEHYDES BY CERIUM(IV) AMMONIUM NITRATE OXIDATION OF UNSYMMETRIC DIMETHYLNAPHTHALENES

When 1,2-,1,3-and 1,6-dimethylnaphthalene are oxidized by Ce(4+) in acetic acid the corresponding monoaldehydes are formed in better than 80percent yield.In each case aldehyde formation takes place with a high degree of selectivity as the methyl-1-to methyl-2-naphthaldehyde ratio is better than 11:1.The selectivity may be explained from differences in reactivity as calculated within the frontier orbital method.