35699-45-7Relevant articles and documents
The influence of aromatic compound protonation on the regioselectivity of Gattermann-Koch formylation
Tanaka, Mutsuo,Fujiwara, Masahiro,Ando, Hisanori,Souma, Yoshie
, p. 159 - 160 (1996)
The regioselectivity of the Gattermann-Koch formylation is influenced by the protonation of aromatic compounds under a solvent-cage-like atmosphere.
FORMATION OF MONOALDEHYDES BY CERIUM(IV) AMMONIUM NITRATE OXIDATION OF UNSYMMETRIC DIMETHYLNAPHTHALENES
Sydnes, Leiv K.,Hansen, Sissel H.,Burkow, Ivan C.,Saethre, Leif J.
, p. 5205 - 5208 (2007/10/02)
When 1,2-,1,3-and 1,6-dimethylnaphthalene are oxidized by Ce(4+) in acetic acid the corresponding monoaldehydes are formed in better than 80percent yield.In each case aldehyde formation takes place with a high degree of selectivity as the methyl-1-to methyl-2-naphthaldehyde ratio is better than 11:1.The selectivity may be explained from differences in reactivity as calculated within the frontier orbital method.
A ONE-POT ORTHO ALKYLATION OF AROMATIC ALDEHYDES
Comins, Daniel L.,Brown, Jack D.,Mantlo, Nathan B.
, p. 3979 - 3982 (2007/10/02)
The addition of aromatic aldehydes to lithium N-methylpiperazide in benzene gave α-amino alkoxides which were ortho-lithiated with excess n-butyllithium.Subsequent alkylation and hydrolysis provided ortho-substituted aromatic aldehydes via a one-pot reaction.