357-28-8 Usage
Physical state
Clear, colorless liquid
Odor
Slightly fruity
Common use
Solvent
Known for
Low toxicity and high stability
Industrial and laboratory applications
Popular choice
Used in production
Pharmaceuticals, agricultural chemicals, and specialty chemicals
Environmental impact
Low
Volatile organic compound (VOC) status
Not considered a VOC
Check Digit Verification of cas no
The CAS Registry Mumber 357-28-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,5 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 357-28:
(5*3)+(4*5)+(3*7)+(2*2)+(1*8)=68
68 % 10 = 8
So 357-28-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H7F5O/c1-3(2)4(12)5(7,8)6(9,10)11/h3H,1-2H3
357-28-8Relevant articles and documents
(Z) -Trifluoromethyl-Trisubstituted Alkenes or Isoxazolines: Divergent Pathways from the Same Allene
Liu, Chaolun,Rowland, Casey A.,Tius, Marcus A.,Yap, Glenn P. A.
supporting information, p. 7208 - 7212 (2020/10/02)
Because of a charge-dipole interaction involving nonbonding electron pairs on fluorine, protonation of trifluoromethyl allenes leads to tri- or tetrasubstituted alkenes with high (Z)-selectivity. Treatment of the same allenes with catalytic Au(I) initiates a reaction cascade that produces isoxazolines in high yield.