35700-21-1 Usage
Description
15(S)-15-Methyl prostaglandin, also known as 15(S)-15-methyl PGF2α, is a synthetic prostaglandin with various biological activities. It is a derivative of prostaglandin F2α (PGF2α) and is characterized by the presence of a methyl group at the 15(S) position. This modification enhances the compound's stability and membrane permeability, making it a versatile molecule for research and therapeutic applications.
Uses
Used in Pharmaceutical Industry:
15(S)-15-Methyl prostaglandin is used as a potent uterine stimulant and abortifacient for [application reason] its ability to induce contractions in the uterus. 15(S)-15-Methyl prostaglandin is particularly effective due to its increased membrane permeability, which allows for better absorption and distribution within the body.
Used in Research Applications:
15(S)-15-Methyl prostaglandin is used as a research tool for [application reason] studying the effects of prostaglandins on various biological processes, including uterine contractions, inflammation, and other physiological responses. Its potent activity makes it a valuable compound for investigating the mechanisms of action and potential therapeutic applications of prostaglandins.
Used in Combination Therapy:
In combination with other drugs like Misoprostol (M368755), 15(S)-15-Methyl prostaglandin is used to enhance human preadipocyte proliferation, up-regulation of glycerolphosphate dehydrogenase (GPDH), and lipid accumulation during differentiation. This application is particularly relevant for research into adipose tissue biology and the development of novel treatments for obesity and related metabolic disorders.
Used in Early Pregnancy Termination:
15(S)-15-Methyl prostaglandin, when used in combination with Carboprost Methyl Ester, has been shown to effectively terminate early pregnancy and exhibit peristatic effects in mice. This application highlights the compound's potential use in reproductive health and family planning.
Used in Pyruvate Dehydrogenase (PDH) Research:
15(S)-15-Methyl prostaglandin is suitable for research related to pyruvate dehydrogenase (PDH), an enzyme complex that plays a crucial role in cellular metabolism. 15(S)-15-Methyl prostaglandin's interaction with PDH-related pathways can provide valuable insights into the regulation of cellular energy production and its implications for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 35700-21-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,7,0 and 0 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35700-21:
(7*3)+(6*5)+(5*7)+(4*0)+(3*0)+(2*2)+(1*1)=91
91 % 10 = 1
So 35700-21-1 is a valid CAS Registry Number.
InChI:InChI=1/C22H38O5/c1-4-5-10-14-22(2,26)15-13-18-17(19(23)16-20(18)24)11-8-6-7-9-12-21(25)27-3/h6,8,13,15,17-20,23-24,26H,4-5,7,9-12,14,16H2,1-3H3/b8-6+,15-13-/t17-,18?,19+,20-,22-/m0/s1
35700-21-1Relevant articles and documents
PROCESS FOR THE PREPARATION OF CARBOPROST AND ITS TROMETHAMINE SALT
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Page/Page column 22-24, (2017/06/24)
The subject of the invention is a novel process for the preparation of Carboprost tromethamine salt where alkylation the enone of the general formula (II) is carried out in the presence of a chiral auxiliary in aprotic solvent with a Grignard reagent. The methyl ester epimers of formula (VII) are separated by gravity silicagel chromatography and the salt formation is carried out by using solid tromethamine base.
8β,12α,15β-PGF2 β Compounds
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, (2008/06/13)
This invention is a group of 8-beta, 12-alpha-PG2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
