35702-19-3Relevant articles and documents
Synthesis of 1′-substituted 4′,4′-dimethyl-6′- methoxy-4′H-spiro[cyclohexane-1,3′-isoquinolines]
Perevoshchikova,Gorbunov,Rozhkova,Slepukhin,Shklyaev
, p. 513 - 517 (2014)
The reaction of 1-(4-methoxyphenyl)-1-(1-methylcyclohexyl)ethanol with nitriles in concentrated sulfuric acid afforded 1′-substituted 6′-methoxy-4′,4′-dimethyl-4′H-spiro[cyclohexane-1, 3′-isoquinolines] as a result of consecutive Wagner-Meerwein rearrangement and Ritter reaction.