35737-10-1 Usage
Description
FMOC-b-Ala-OH, also known as 9-fluorenylmethoxycarbonyl-beta-alanine, is a synthetic compound that serves as a crucial building block in the field of organic synthesis. It is a white to light yellow crystalline powder with unique chemical properties that make it valuable in various applications.
Uses
Used in Organic Synthesis:
FMOC-b-Ala-OH is used as a key intermediate for the synthesis of various organic compounds. Its chemical structure allows for the formation of new bonds and the creation of complex molecules, making it an essential component in the development of novel organic compounds.
Used in Pharmaceutical Industry:
FMOC-b-Ala-OH is used as a building block for the synthesis of pharmaceutical compounds. Its incorporation into drug molecules can enhance their efficacy, stability, and bioavailability, leading to the development of more effective medications.
Used in Agrochemicals:
In the agrochemical industry, FMOC-b-Ala-OH is used as a starting material for the development of new pesticides and herbicides. Its unique properties enable the creation of compounds with improved activity and selectivity, contributing to more effective and environmentally friendly agricultural products.
Used in Dyestuffs:
FMOC-b-Ala-OH is used as a raw material in the production of dyes and pigments. Its chemical structure can be modified to create a wide range of colors, making it a versatile component in the dyestuffs industry.
Check Digit Verification of cas no
The CAS Registry Mumber 35737-10-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,7,3 and 7 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 35737-10:
(7*3)+(6*5)+(5*7)+(4*3)+(3*7)+(2*1)+(1*0)=121
121 % 10 = 1
So 35737-10-1 is a valid CAS Registry Number.
InChI:InChI=1/C18H17NO4/c20-17(21)9-10-19-18(22)23-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2,(H,19,22)(H,20,21)/p-1
35737-10-1Relevant articles and documents
Unwanted hydrolysis or α/β-peptide bond formation: How long should the rate-limiting coupling step take?
Goldschmidt G?z, Viktória,Nagy, Adrienn,Farkas, Viktor,Keszei, Ern?,Perczel, András
, p. 30720 - 30728 (2019/10/28)
Nowadays, in Solid Phase Peptide Synthesis (SPPS), being either manual, automated, continuous flow or microwave-assisted, the reaction with various coupling reagents takes place via in situ active ester formation. In this study, the formation and stability of these key active esters were investigated with time-resolved 1H NMR by using the common PyBOP/DIEA and HOBt/DIC coupling reagents for both α- and β-amino acids. Parallel to the amide bond formation, the hydrolysis of the α/β-active esters, a side reaction that is a considerable efficacy limiting factor, was studied. Based on the chemical nature/constitution of the active esters, three amino acid categories were determined: (i) the rapidly hydrolyzing ones (t 24 h) in solution. The current insight into the kinetics of this key hydrolysis side reaction serves as a guide to optimize the coupling conditions of α- and β-amino acids, thereby saving time and minimizing the amounts of reagents and amino acids to be used-all key factors of more environmentally friendly chemistry.
