35740-83-1

Basic information

• Product Name: 2-bromo-3-(bromomethyl)quinoline
• Synonyms: 2-bromo-3-(bromomethyl)quinoline
• CAS NO: 35740-83-1
• Molecular Formula: C₁₀H₇Br₂N
• Molecular Weight: 300.97728
• Mol File: 35740-83-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 137-138 °C
• Boiling Point: 368.5±27.0 °C(Predicted)
• Appearance: /
• Density: 1.852±0.06 g/cm3(Predicted)
• PKA: -0.50±0.50(Predicted)
• CAS DataBase Reference: 2-bromo-3-(bromomethyl)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-3-(bromomethyl)quinoline(35740-83-1)
• EPA Substance Registry System: 2-bromo-3-(bromomethyl)quinoline(35740-83-1)

Safety Data

• Hazardous Substances Data: 35740-83-1(Hazardous Substances Data)

Upstream product

• 73568-25-9 2-chloro-3-quinoline carboxaldehyde 
• 125917-60-4 2-chloro-3-(hydroxymethyl)quinoline 

Downstream Products

• 292077-58-8 C-(2-Bromoquinolin-3-yl)methylamine 
• 916755-34-5 3-benzyloxymethyl-1-(2-bromoquinolin-3-ylmethyl)-4-(1-ethylpropenyl)-1H-pyridin-2-one 
• 205989-13-5 quino[2',3':3,4]pyrrolo[2,1-b]quinazolin-13-hydroxy-11-one 
• 30062-37-4 indolizino[1,2-b]quinolin-9(11H)-one 
• 55854-89-2 8-methyl-7-propionylindolizino[1,2-b]quinoline-9(11H)-one 
• 620962-75-6 7-trifluoroacetyl-6,8-dihydro-6-(phenylthiomethyl)pyrrolo[3,4-b]quinoline 
• 620962-73-4 N-(2-bromoquinolin-3-yl)methyl-N-[2,2-bis(phenylthio)ethenyl]amine 
• 620962-76-7 7-(2-methyl-4-oxohexanoyl)-6,8-dihydro-6-(phenylthiomethyl)pyrrolo[3,4-b]quinoline 
• 620962-77-8 7-(2-methyl-4-oxohexanoyl)-6,8-dihydro-6-(phenylsulfinylmethyl)pyrrolo[3,4-b]quinoline 
• 620962-81-4 7-(2-methyl-4-oxohex-2-enoyl)-6,8-dihydro-6-(phenylthiomethyl)pyrrolo[3,4-b]quinoline 
• 620962-82-5 7-(2-methyl-4-oxohex-2-enoyl)-6,8-dihydro-6-(phenylsulfinylmethyl)pyrrolo[3,4-b]quinoline 
• 620962-74-5 N-(2-bromoquinolin-3-yl)methyl-N-[2,2-bis(phenylthio)ethenyl]trifluoroacetamide 
• 7689-03-4 camptothecin 

Relevant articles and documents

Enantioselective Palladium-Catalyzed Heck-Heck Cascade Reactions: Ready Access to the Tetracyclic Core of Lycorane Alkaloids

A rapid and efficient access to a wide variety of enantiomerically enriched C-11b substituted lycorane analogues can be achieved via a catalytic asymmetric Heck-Heck 6-exo/6-endo cascade reaction in the presence of (R)-BINAP.

Intramolecular cyclisation of functionalised heteroaryllithiums. Synthesis of novel indolizinone-based compounds

The intramolecular cyclisation of heteroaryllithiums derived from N-heteroarylmethylpyrrole-2-carboxamides takes place smoothly at low temperature when N-methoxy-N-methyl and morpholine amides are used as internal electrophiles. Halogen-lithium exchange using n-BuLi is the method of choice to achieve metalation on the quinoline and pyridine derivatives, while directed lithiation (LDA) works better for furan. In the case of thiophene both methodologies can be applied. These metalation-cyclisation sequences provide a useful entry to several types of indolizidine based compounds (pyrrolo[1,2-b]acridinones, pyrrolo[1,2-g]quinolones, thieno and furo[3,2-f]indolizinones).