357400-76-1

Basic information

• Product Name: methyl 4-(5,5-dicyano-3-methoxycarbonylpentyl)benzoate
• Synonyms: methyl 4-(5,5-dicyano-3-methoxycarbonylpentyl)benzoate
• CAS NO: 357400-76-1
• Molecular Weight: 314.341
• Mol File: 357400-76-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-(5,5-dicyano-3-methoxycarbonylpentyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(5,5-dicyano-3-methoxycarbonylpentyl)benzoate(357400-76-1)
• EPA Substance Registry System: methyl 4-(5,5-dicyano-3-methoxycarbonylpentyl)benzoate(357400-76-1)

Safety Data

• Hazardous Substances Data: 357400-76-1(Hazardous Substances Data)

Upstream product

• 4224-69-5 methyl 2-(bromomethyl)propenoate 
• 109-77-3 malononitrile 
• 213256-74-7 methyl p-(3-methoxycarbonyl-3-butenyl)benzoate 

Downstream Products

• 213256-78-1 methyl 4-[2-(2,4-diamino-7-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-6-yl)ethyl]benzoate 
• 213256-82-7 4-[2-(2,4-Diamino-7-oxo-5,6,7,8-tetrahydro-pyrido[2,3-d]pyrimidin-6-yl)-ethyl]-benzoic acid 
• 213256-87-2 (S)-2-{4-[2-(2,4-Diamino-7-oxo-5,6,7,8-tetrahydro-pyrido[2,3-d]pyrimidin-6-yl)-ethyl]-benzoylamino}-pentanedioic acid dimethyl ester 

Relevant articles and documents

Selective reduction of the 7-oxo group in pyrido[2,3d]pyrimidine-4,7- diones: A new synthetic approach to 5,10-dideazatetrahydrofolic acid (DDATHF)

A selective reduction of the carbonyl group at C7 with borane in THF is accomplished for 2,4-diamino-7-oxo and 2-amino-4,7-dioxo substituted pyridopyrimidines (7a-c) and (13a-c) respectively, the ester group remaining unaltered in both cases. The synthesi