357413-57-1Relevant articles and documents
Potent and selective carboxylic acid-based inhibitors of matrix metalloproteinases
Pikul,Ohler,Ciszewski,Laufersweiler,Almstead,De,Natchus,Hsieh,Janusz,Peng,Branch,King,Taiwo,Mieling
, p. 2499 - 2502 (2001)
A novel series of carboxylic acids containing a substituted piperidine were synthesized and tested for inhibition of selected matrix metalloproteinases. Multiple analogues prepared based on this novel design were found to inhibit the target MMPs (MMP-2,-3