357615-60-2

Basic information

• Product Name: C₂₃H₂₃N₇O₇S₂
• Synonyms: C₂₃H₂₃N₇O₇S₂
• CAS NO: 357615-60-2
• Molecular Weight: 573.61
• Mol File: 357615-60-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₃N₇O₇S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₃N₇O₇S₂(357615-60-2)
• EPA Substance Registry System: C₂₃H₂₃N₇O₇S₂(357615-60-2)

Safety Data

• Hazardous Substances Data: 357615-60-2(Hazardous Substances Data)

Upstream product

• 4083-64-1 Tosyl isocyanate 
• 144486-49-7 [5-Amino-1-(2-hydroxy-ethyl)-1H-imidazol-4-yl]-imino-acetonitrile 

Relevant articles and documents

A new and efficient approach to the synthesis of 6-amidino-2-oxopurines

The reaction of 5-amino-4-cyanoformimidoylimidazoles 1a and 1b with tosyl isocyanate proved to be a mild and efficient method for the synthesis of the corresponding 6-amidino-2-oxopurines 5. These compounds, which were isolated in almost quantitative yield, rearrange in the presence of acetic acid-DMF to give a pyrimido[5,4-d]-pyrimidin-2-one 6. The structure of compound 6 was confirmed by X-ray crystallography. The pathway for both reactions is discussed. Studies on the reactivity of tosyl isocyanate with imidazoles 2, 7, 8 and 16, obtained from 1 by selective acylation of the amino or imino nitrogen atoms, enabled clarification of the mechanism for purine formation.