35776-96-6

Basic information

• Product Name: 4-(4-methylbenzoyl)benzoic acid
• CAS NO: 35776-96-6
• Molecular Formula: C₁₅H₁₂O₃
• Molecular Weight: 240.254
• Mol File: 35776-96-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 444°C at 760 mmHg
• Flash Point: 236.5°C
• Density: 1.223g/cm³
• Vapor Pressure: 1.15E-08mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: 4-(4-methylbenzoyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-methylbenzoyl)benzoic acid(35776-96-6)
• EPA Substance Registry System: 4-(4-methylbenzoyl)benzoic acid(35776-96-6)

Safety Data

• Hazardous Substances Data: 35776-96-6(Hazardous Substances Data)

Upstream product

• 611-97-2 bis(p-methylphenyl)-methanone 
• 530-45-0 1,1-di(4-methylphenyl)ethane 
• 7377-26-6 4-Methoxycarbonylbenzoyl chloride 
• 108-88-3 toluene 
• 64141-11-3 (4-(methoxycarbonyl)phenyl)(4-methylphenyl)methanone 
• 100-20-9 terephthaloyl chloride 
• 64-19-7 acetic acid 
• 5432-01-9 1,1-dichloro-2,2-bis(4-tolyl)ethene 
• 4957-14-6 4,4'-dimethyldiphenylmethane 
• 67-56-1 methanol 
• 71616-80-3 tert-butyl 4-(4'-methylbenzoyl)perbenzoate 
• 71-43-2 benzene 
• 88641-79-6 tert-butyl 4-(4'-bromomethylbenzoyl)perbenzoate 

Downstream Products

• 64141-11-3 (4-(methoxycarbonyl)phenyl)(4-methylphenyl)methanone 
• 35776-97-7 4-(4'-methylbenzoyl)benzoyl chloride 
• 71616-80-3 tert-butyl 4-(4'-methylbenzoyl)perbenzoate 
• 88641-79-6 tert-butyl 4-(4'-bromomethylbenzoyl)perbenzoate 
• 460062-23-1 tert-butyl 4-(4'-chloromethylbenzoyl)perbenzoate 

Relevant articles and documents

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Use of src SH2 specific compounds to treat a bone resorption disease

Invented is a method of treating a bone resorption disease in a subject which comprises administering to the subject a therapeutically effective amount of a compound which binds to a human src SH2 domain with a binding affinity greater than fifty-fold higher than the binding affinity with which the compound binds to a human lck SH2 domain and a human fyn SH2 domain, and, binds to a human hcp SH2 domain, a human Grb2 SH2 domain, a human SH-PTP2 SH2 domain and a human p85 SH2 domain with a binding affinity which is greater than fifty-fold lower than the binding affinity with which the compound binds to such src SH2 domain.

Effect of Chain Length on Mesomorphism of Steroid Esters of 4-(4-Alkylphenyl-X)benzoic Acids with X = CO, O, S, and CH2

To examine the effect of bent shapes on mesomorphic properties a homologous series of steroid esters have been prepared: H(CH2)n-4-C6H4-X-4-C6H4COOR, X = CO, O, S, CH2, R = cholesteryl, β-sitosteryl, cholestanyl, stigmasteryl, ergosteryl; n = 0-15.The chain elongation results in an increase in not only the molecular length but also the breadth due to the angular linkage, X.The steroid portions are of primary importance for the mesomorphic properties of the present series, and the thermal stability of the mesophases is strongly dependent on the mesogenic power of the aryl portions, where the effective order is CO > O > S > CH2.The transition enthalpies and entropies for the smectic A-cholesteric and cholesteric-isotropic (Ch-I) transitions are almost independent of the chain length of the alkyl group, indicating that a long alkyl chain has no role from a thermodynamical piont of view.Within the mesophases, the aryl and steroid cores are assumed to be piled up, interacting with each other, and the alkyl groups are apart from each other to avoid short-range interaction.