35808-40-3

Basic information

• Product Name: 1,2,3,4-TETRAHYDRO-PYRIDO[2,3-B]PYRAZINE
• Synonyms: 1,2,3,4-TETRAHYDRO-PYRIDO[2,3-B]PYRAZINE;Pyrido[2,3-b]pyrazine, 1,2,3,4-tetrahydro-
• CAS NO: 35808-40-3
• Molecular Formula: C₇H₉N₃
• Molecular Weight: 135.17
• Mol File: 35808-40-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 318.508°C at 760 mmHg
• Flash Point: 146.429°C
• Appearance: /
• Density: 1.112g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 1,2,3,4-TETRAHYDRO-PYRIDO[2,3-B]PYRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-TETRAHYDRO-PYRIDO[2,3-B]PYRAZINE(35808-40-3)
• EPA Substance Registry System: 1,2,3,4-TETRAHYDRO-PYRIDO[2,3-B]PYRAZINE(35808-40-3)

Safety Data

• Hazardous Substances Data: 35808-40-3(Hazardous Substances Data)

Usage

Uses

1,2,3,4-Tetrahydropyrido[2,3-B]pyrazine can be used as SHP2 phosphatase inhibitors.

InChI:InChI=1/C7H9N3/c1-2-6-7(9-3-1)10-5-4-8-6/h1-3,8H,4-5H2,(H,9,10)

Upstream product

• 322-46-3 5-azaquinoxaline 
• 452-58-4 2,3-Diaminopyridine 
• 107-21-1 ethylene glycol 

Relevant articles and documents

An annulative transfer hydrogenation strategy enables straightforward access to tetrahydro fused-pyrazine derivatives

A ruthenium-catalysed annulative transfer hydrogenation strategy, enabling straightforward access to tetrahydro fused-pyrazine derivatives from N-heteroaryl diamines and vicinal diols, has been demonstrated for the first time. Such a synthesis proceeds with unprecedented synthetic effectiveness including high step- and atom efficiency, generation of water as the sole by-product, short reaction time and no need for external high pressure H2 gas, offering an important basis for the transformation of vicinal diols, a class of bio-mass derived resources, into functionalized products.