35823-28-0

Basic information

• Product Name: N-[(1-methyl)phenylmethyl]imino-acetic acid ethyl ester
• Synonyms: N-[(1-methyl)phenylmethyl]imino-acetic acid ethyl ester
• CAS NO: 35823-28-0
• Molecular Weight: 205.257
• Mol File: 35823-28-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-[(1-methyl)phenylmethyl]imino-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(1-methyl)phenylmethyl]imino-acetic acid ethyl ester(35823-28-0)
• EPA Substance Registry System: N-[(1-methyl)phenylmethyl]imino-acetic acid ethyl ester(35823-28-0)

Safety Data

• Hazardous Substances Data: 35823-28-0(Hazardous Substances Data)

Upstream product

• 924-44-7 glyoxylic acid ethyl ester 
• 618-36-0 rac-methylbenzylamine 

Downstream Products

• 869658-19-5 2-aza-2-(1-phenylethyl)-3-ethoxycarbonyl-<2,2,2>-bicyclooct-5-ene 

Relevant articles and documents

Method for the synthesis of 4-hydroxyisoleucine and the derivatives thereof

The invention relates to a method for the synthesis of two isomers, at function OH, alone or in mixtures, of amino acids α or the derivatives thereof, having general formula (B), wherein: linkage C—O of the 4-position carbon (represented by symbol) denotes one or other of isomers III or IV, or mixtures thereof. Moreover, R1 and R2 represent: a hydrogen atom; or either R1 or R2 represents a hydrogen atom and the other substituent is a radical Ra, an acyl group —CORa, such as acetyl, or a functional group —COORa, —SO2Ra, —N (Ra, Rb), Ra and Rb, which are identical or different, representing a C1-C12 linear or branched alkyl radical, optionally substituted, an aryl group with one or more aromatic rings and heterocycles, comprising between 5 and 8C, optionally substituted, or aralkyl, the alkyl substituent and the aryl group being as defined above; or R1 and R2 both represent a substituent as defined above. R3 represents a hydrogen atom or Ra and R4 has the significance of Ra. The invention is characterised in that it comprises: the isomerisation of a compound having formula (I), wherein R1, R2, Ra, R3 and R4 are as defined above, such as to produce a compound having formula (II); and the reduction of the carbonyl function thereof which, depending on the catalytic system employed and the formula (I) compound used, produces one of the isomers having general formula (III) or (IV) or a mixture thereof having formula (B). The invention can be used for the synthesis of (2S, 3R, 4S)-4-hydroxyisoleucine.

SUBSTITUTED 2-ARYLCARBONYLOXYMETHYL-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF

Substituted 2-arylcarbonyloxymethyl-1,2,5-thiadiazolidin-3-one 1,1-dioxide derivatives, pharmaceutical compositions containing them and methods for the treatment of degenerative diseases utilizing them.