358674-74-5

Basic information

• Product Name: N-(4-n-propylphenyl)piperazine
• Synonyms: N-(4-n-propylphenyl)piperazine
• CAS NO: 358674-74-5
• Molecular Weight: 204.315
• Mol File: 358674-74-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(4-n-propylphenyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-n-propylphenyl)piperazine(358674-74-5)
• EPA Substance Registry System: N-(4-n-propylphenyl)piperazine(358674-74-5)

Safety Data

• Hazardous Substances Data: 358674-74-5(Hazardous Substances Data)

Upstream product

• 1121596-48-2 4-(4-propyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 110-85-0 piperazine 
• 588-93-2 p-bromo-n-propylbenzene 

Relevant articles and documents

GLP-1 RECEPTOR MODULATORS

Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where "^^^^" represents either or both the R and S form of the compound) (I) where A, B, C, Y1, Y2, Z, R1, R2, R3, R4, R5, W1, n, p and q are as defined herein.

Synthesis of potent and selective dopamine D4 antagonists as candidate radioligands

A series of dopamine D4 antagonists was synthesized and evaluated as potential candidates for development as positron emission tomography (PET) radioligands. All new compounds display high affinity and selectivity for the D4 receptors and compounds 5b, 5d, and 5e were identified as candidates for radioligand development.