358780-22-0

Basic information

• Product Name: N-[[6-(trifluoromethyl)-3-pyridinyl-amino]thioxomethyl]benzamide
• CAS NO: 358780-22-0
• Molecular Weight: 325.314
• Mol File: 358780-22-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[[6-(trifluoromethyl)-3-pyridinyl-amino]thioxomethyl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[[6-(trifluoromethyl)-3-pyridinyl-amino]thioxomethyl]benzamide(358780-22-0)
• EPA Substance Registry System: N-[[6-(trifluoromethyl)-3-pyridinyl-amino]thioxomethyl]benzamide(358780-22-0)

Safety Data

• Hazardous Substances Data: 358780-22-0(Hazardous Substances Data)

Upstream product

• 532-55-8 Benzoyl isothiocyanate 
• 106877-33-2 6-(trifluoromethyl)pyridin-3-amine 

Relevant articles and documents

2,4-Disubstituted thiazolyl derivatives

This invention concerns the use of a compound of formula (I′) a N-oxide, pharmaceutically acceptable addition salt, quaternary amine and stereochemically isomeric form thereof, wherein Q is optionally substituted C3-6cycloalkyl, phenyl, naphthyl, pyridyl, pyrimidinyl, pyrazinyl, pyridazinyl, benzthiazolyl, benzoxazolyl, benzimidazolyl, indazolyl, or imidazopyridyl; or Q is a radical of formula wherein X and Y each independently are O, NR3, CH2 or S, with R3 being hydrogen or C1-4alkyl; q is 1 to 4; Z is O or NR4 with R4 being hydrogen or C1-4alkyl; r is 1 to 3; L is optionally substituted phenyl or L is Het with Het being an optionally substituted five- or six-membered heterocyclic ring or an optionally substituted bicyclic heterocyclic ring; for the manufacture of a medicament for the prevention or the treatment of diseases mediated through cytokines.