358789-49-8Relevant articles and documents
2,4-Di(hetero-)arylamino(-oxy)-5-substituted pyrimidines as antineoplastic agents
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, (2008/06/13)
Pyrimidine derivatives of formula (I) wherein Q1, Q2, G and R1 are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.