3591-19-3

Basic information

• Product Name: 3,3-(Dimethoxy)-5α-androstan-17-one
• Synonyms: 3,3-(Dimethoxy)-5α-androstan-17-one;3,3-Dimethoxy-5α-androsta-17-one;3,3-Dimethoxy-5α-androstan-17-one
• CAS NO: 3591-19-3
• Molecular Formula: C21H34O3
• Molecular Weight: 334.49286
• Mol File: 3591-19-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,3-(Dimethoxy)-5α-androstan-17-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-(Dimethoxy)-5α-androstan-17-one(3591-19-3)
• EPA Substance Registry System: 3,3-(Dimethoxy)-5α-androstan-17-one(3591-19-3)

Safety Data

• Hazardous Substances Data: 3591-19-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 846-46-8 androstanedione 
• 63-05-8 4-androstene-3,17-dione 
• 4966-70-5 Androsten-⁽⁵⁾-dion-(3,17)-bis-aethylenacetal 
• 846-46-8 androstanedione 

Downstream Products

• 846-46-8 (5ξ)-androstane-3,17-dione 
• 300351-07-9 17α-[(N-4-azido-2-nitrophenyl)amidomethyl]-17β-hydroxy-5α-androstan-3-one 
• 300351-06-8 17α-[(N-4-azido-2-nitrophenyl)aminomethyl]-3,3-dimethoxy-5α-androstan-17β-ol 
• 300351-10-4 17α-[(N-4-azido-2-nitrophenyl)aminoethyl]-17β-hydroxy-5α-androstan-3-one 
• 300350-98-5 17α-[(N-5-azido-2-nitrobenzoyl)amidomethyl]-17β-hydroxy-5α-androstan-3-one 
• 300351-09-1 17α-[(N-4-azido-2-nitrophenyl)aminoethyl]-3,3-dimethoxy-5α-androstan-317β-ol 
• 300351-13-7 17α-[(N-4-azido-2-nitrophenyl)aminopropyl]-17β-hydroxy-5α-androstan-3-one 
• 300351-12-6 17α-[(N-4-azido-2-nitrophenyl)aminopropyl]-3,3-dimethoxy-5α-androstan-17β-ol 
• 300351-01-3 17α-[(N-5-azido-2-nitrobenzoyl)amidoethyl]-17β-hydroxy-5α-androstan-3-one 
• 300350-97-4 17α-[(N-5-azido-2-nitrobenzoyl)amidomethyl]-3,3-dimethoxy-5α-androstan-17β-ol 
• 300351-03-5 17α-[(N-5-azido-2-nitrobenzoyl)amidopropyl]-3,3-dimethoxy-5α-androstane-17β-ol 
• 300351-04-6 17α-[(N-5-azido-2-nitrobenzoyl)amidopropyl]-17β-hydroxy-5α-androstan-3-one 
• 300351-00-2 17α-[(N-5-azido-2-nitrobenzoyl)amidoethyl]-3,3-dimethoxy-5α-androstan-17β-ol 
• 300351-16-0 17α-[(N-5-azido-2-nitro-3,4,6-trifluorophenyl)aminomethyl]-17β-hydroxy-5α-androstan-3-one 

Relevant articles and documents

Method for synthesizing stanozolol intermediate androstane-17alpha-methyl-17beta-hydroxyl-3-ketone

The invention provides a method for synthesizing a stanozolol intermediate androstane-17alpha-methyl-17beta-hydroxyl-3-ketone. The method comprises the following steps: taking 4-androstenedione as a raw material, carrying out 3-site and 17-site keto-double-ketal, 5-site ethylenic bond catalytic hydrogenation and 3-site and 17-site double-ketal hydrolysis to prepare a compound 5alpha-androstane-3,17-diketone; then carrying out 3-site keto-double-etherification and 17-site Grignard addition, and finally carrying out hydrolysis to prepare the compound androstane-17alpha-methyl-17beta-hydroxyl-3-ketone, wherein the HPLC (High Performance Liquid Chromatography) purity of the compound is 99.0% or greater. The method provided by the invention is short in route, easy in production process control,environmentally-friendly, low in production cost and applicable to industrial large-scale production.

Synthesis and substance P receptor binding activity of androstano[3,2- b]pyrimido[1,2-a]benzimidazoles

Several heterosteroids containing a dihydroethisterone skeleton were prepared and shown to displace substance P in a receptor binding assay. Further biochemical (kinetic and Scatchard analyses) and pharmacological evaluation (substance P-induced plasma extravasation and salivation in the rat) of a representative example in this series (5a) established that these compounds are competitive antagonists at the substance P receptor.

Synthesis of 17-hydroxyimino steroids and their O-alkyl derivatives.

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