3593-24-6

Basic information

• Product Name: N,N,N-tripropylbutan-1-aminium iodide
• CAS NO: 3593-24-6
• Molecular Formula: C₁₃H₃₀IN
• Molecular Weight: 327.2885
• Mol File: 3593-24-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N,N-tripropylbutan-1-aminium iodide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N,N-tripropylbutan-1-aminium iodide(3593-24-6)
• EPA Substance Registry System: N,N,N-tripropylbutan-1-aminium iodide(3593-24-6)

Safety Data

• Hazardous Substances Data: 3593-24-6(Hazardous Substances Data)

Upstream product

• 107-10-8 propylamine 
• 542-69-8 1-iodo-butane 
• 4444-71-7 N,N-dipropylbutylamine 
• 107-08-4 1-iodo-propane 
• 102-69-2 tri-n-propylamine 

Relevant articles and documents

Quaternary ammonium ions can externally block voltage-gated K+ channels. Establishing a theoretical and experimental model that predicts KDS and the selectivity of K+ over Na+ ions

The physicochemical basis for the high ion selectivity of potassium channels is poorly understood. In the present studies, external blockade of cloned voltage-gated potassium channels with alkyl quaternary ammonium ions are analyzed from a model derived from theory and experimental data. Atomic mass units, electrostatic potential residing on the nitrogen atom, the COSMO van der Waals solvent accessible surface, the Onsager solvation model, and the isodensity PCM solvation model are computed at the semi-empirical and the ab initio levels of theory. A structure-activity relationship (SAR) exists between the calculated values and the experimentally obtained KD (mM). The SAR model gives us KD predictions and when K+ and Na+ are incorporated into the model, it dramatically predicts the selectivity of K+ over Na+ ions.