35931-31-8

Basic information

• Product Name: nicotinic acid (4-allyl-2-methoxy)phenyl ester
• Synonyms: nicotinic acid (4-allyl-2-methoxy)phenyl ester
• CAS NO: 35931-31-8
• Molecular Weight: 269.3
• Mol File: 35931-31-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: nicotinic acid (4-allyl-2-methoxy)phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: nicotinic acid (4-allyl-2-methoxy)phenyl ester(35931-31-8)
• EPA Substance Registry System: nicotinic acid (4-allyl-2-methoxy)phenyl ester(35931-31-8)

Safety Data

• Hazardous Substances Data: 35931-31-8(Hazardous Substances Data)

Upstream product

• 97-53-0 4-allylguaiacol 
• 20260-53-1 pyridine-3-carbonyl chloride hydrochloride 
• 10400-19-8 3-pyridinecarbonyl chloride 

Relevant articles and documents

Design and synthesis of eugenol derivatives, as potent 15-lipoxygenase inhibitors

A group of 4-allyl-2-methoxyphenol (eugenol) esters were designed, synthesized, and evaluated as potential inhibitors of soybean 15-lipoxygenase (SLO). Compounds 4c, 4d 4f, 4p, and 4q showed the best IC50 in SLO inhibition (IC50 = 1.7, 2.3, 2.1, 2.2, and 0.017 μM, respectively). All compounds were docked into SLO active site and showed that allyl group of compounds is oriented toward the iron atom in the active site of SLO. It is assumed that lipophilic interaction of ligand-enzyme would be in charge of inhibiting the enzyme activity. The selectivity of eugenol derivatives in inhibiting 15-HLOb was also compared with 15-HLOa by molecular modeling and multiple alignment techniques.