35958-64-6Relevant articles and documents
INHIBITORS OF MALARIAL AND PLASMODIUM FALCIPARUM HEXOSE TRANSPORTER AND USES THEREOF
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Paragraph 00510, (2021/08/14)
Provided are molecules capable of binding to binding pockets of Plasmodium falciparum hexose transporter (PfHT) or analogs thereof and complexes comprising the same. Also provided herein are inhibitors of PfHT, pharmaceutical compositions comprising the i
Synthesis, antiproliferative activity and SAR analysis of (?)-cleistenolide and analogues
Benedekovi?, Goran,Popsavin, Mirjana,Kova?evi?, Ivana,Koji?, Vesna,Rodi?, Marko,Popsavin, Velimir
, (2020/07/15)
A new, modified total synthesis of (?)-cleistenolide (1) and sixteen new analogues or derivatives was achieved starting from commercially available 1,2-O-isopropylidene-α-D-glucofuranose. The synthesis of 1 proceeds in six steps and 67% overall yield, usi
First synthesis of 4a-carba-β-d-galactofuranose
Frigell, Jens,Cumpstey, Ian
, p. 9073 - 9076 (2008/03/27)
The synthesis of 4a-carba-β-d-galactofuranose is described starting from diacetone glucose. The key ring-closure step was carried out by metathesis to form a cyclopentene. Catalytic hydrogenation of the C{double bond, long}C double bond gave the galacto configured saturated carbahexofuranose with excellent diastereoselectivity.