35980-64-4

Basic information

• Product Name: Benzenesulfonamide, 4-methyl-N,N-bis[3-[[(4-methylphenyl)sulfonyl]amino]propyl]-
• Synonyms: N,N',N''-TRI-P-TOSYL-3,3'-IMINOBISPROPYLAMINE;N,N′,N′′-TRI-P-TOSYL-3,3′-IMINOBISPROPYLAMINE
• CAS NO: 35980-64-4
• Molecular Formula: C27H35N3O6S3
• Molecular Weight: 593.789
• Mol File: 35980-64-4.mol
• Article Data: 17

Chemical Properties

• Melting Point: 52-54 °C
• Boiling Point: 756.3±70.0 °C(Predicted)
• Density: 1.291±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenesulfonamide, 4-methyl-N,N-bis[3-[[(4-methylphenyl)sulfonyl]amino]propyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-methyl-N,N-bis[3-[[(4-methylphenyl)sulfonyl]amino]propyl]-(35980-64-4)
• EPA Substance Registry System: Benzenesulfonamide, 4-methyl-N,N-bis[3-[[(4-methylphenyl)sulfonyl]amino]propyl]-(35980-64-4)

Safety Data

• Hazardous Substances Data: 35980-64-4(Hazardous Substances Data)

Upstream product

• 56-18-8 bis(3-aminopropyl)amine 
• 98-59-9 p-toluenesulfonyl chloride 
• 7732-18-5 water 
• 124040-14-8 N¹-formyl-N⁷,N⁷-phthaloyl-4-tosyl-4-azaheptane-1,7-diamine 
• 121821-23-6 N¹,N⁷-diformyl-4-tosyl-4-azaheptane-1,7-diamine 
• 120239-63-6 N,N,N',N'-tetra(3-aminopropyl)-1,4-butanediamine 

Downstream Products

• 74461-32-8 4,8,12-tris(p-tolylsulphonyl)-1-oxa-4,8,12-triazacyclotetradecane 
• 108603-01-6 1,4,7,10,14-pentatosyl-1,4,7,10,14-pentaazacycloheptadecane 
• 35980-66-6 N,N',N''-tritosyl-1,4,8-triazacycloundecane 
• 60147-31-1 7,11,15-tris(p-tolylsulphonyl)-1,4-dioxa-7,11,15-triazacycloheptadecane 
• 35980-67-7 1,5,9-tritosyl-1,5,9-triazacyclododecane 
• 115368-18-8 C₂₉H₃₉N₃O₇S₃ 
• 52877-36-8 1,4,7,11-tetra-azacyclotetradecane 
• 74676-52-1 1,5,9-triazacyclotridecane 
• 125683-05-8 3,7,11,19,27-pentatosyl-3,7,11,19,27,33,34,35-octaazatetracyclo<27.3.1.1^13,17.1^21,25>pentatriaconta-1(33),13(34),14,16,21(35),22,24,29,31-nonaene 
• 125682-99-7 1,11-bis<<6-<(mesyloxy)methyl>pyridin-2-yl>methyl>-2,6,10-tritosyl-2,6,10-triazaundecane 
• 125682-98-6 1,11-bis<6-(hydroxymethyl)pyridin-2-yl>-2,6,10-tritosyl-2,6,10-triazaundecane 
• 125683-01-4 3,6,9,17,21,25-hexatosyl-3,6,9,17,21,25,31,32-octaazatricyclo<25.3.1.1^1,15>dotriaconta-1(31),11(32),12,14,27,29-hexaene 
• 76980-38-6 N,N',4,8,12-penta(p-toluenesulfonyl)-4,8,12-triazapentadecane-1,15-diamine 
• 76980-35-3 1,15-di(methanesulfonyloxy)-4,8,12-tri(p-toluenesulfonyl)-4,8,12-triazapentadecane 

Relevant articles and documents

Towards a selective functionalization of ammo-terminated dendrimers

Selective functionalization of the periphery of commercial polypropyleneamine (POPAM) and polyamidoamine (PAMAM) dendrimers has been investigated in preparative scale. The first generation (Gl) POPAM dendrimer was for the first time selectively N,N-bis(sulfonylated) with tosyl chloride and the corresponding mono-, di-, tri-, and tetra-N-tosylsulfonamides were isolated and fully characterized. Unexpectedly, similar persulfonylation of G2 POPAM results in splitting of a central C-N bond and only fully and partially sulfonylated halves of the initial dendrimer could be isolated. Higher generations of POPAM are also split during the persulfonylation yielding complex mixtures of persulfonylated dendritic fragments which could hardly be identified. A plausible mechanism of the POPAM decomposition on the basis of the reaction product analysis is proposed. N-Sulfonylation of a peripheral octasulfonamide of G2 POPAM with tosyl chloride also leads to the destruction of the dendrimer, while its N-alkylation with benzyl bromide proved to be not selective yielding a completely alkylated derivative. Unlike POPAM dendrimers, PAMAM dendrimers were shown to be more stable during their sulfonylation and no decomposition of the dendritic backbone was detected. In contrast to the POPAM dendrimers, PAMAM dendrimers were shown to be rather inert with respect to the formation of N-tosylsulfonamides since they could only be N-monosulfonylated at all peripheral amino groups. The combination of MALDI-TOF and ESI-FT-ICR tandem mass spectrometry has been shown to be an effective method for structure assignment and purity check of selectively or fully persulfonylated dendritic oligoamines. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

16-Member ring metal chelate

Metal chelates are useful for improving the contrast of X-ray, ultrasound, radionuclide and magnetic resonance (MR) images. However, the metal complexes must be stable and inert so that toxicity resulting from dissociation in the body can be minimized. This invention provides 16-member ring metal chelates that can provide a charge balanced metal complex having improved stability, especially for gadolinium(III) and samarium (III).

Fine-tuning the electronic properties of highly stable organometallic CuIII complexes containing monoanionic macrocyclic ligands

A family of highly stable organometallic CuIII complexes with monoanionic triazamacrocyclic ligands (L′) with general formula [CuL′]+ have been prepared and isolated, and their structural, spectroscopic, and redox properties thorough