360048-63-1 Usage
Description
(R)-(-)-1-[(S)-2-(DI(3,5-DIMETHYL-4-METHOXYPHENYL)PHOSPHINO)FERROCENYL]ETHYLDICYCLOHEXYLPHOSPHINE is a complex organic compound with a unique structure that features a chiral phosphine ligand. It is an orange powder and is sold in collaboration with Solvias AG. (R)-(-)-1-[(S)-2-(DI(3,5-DIMETHYL-4-METHOXYPHENYL)PHOSPHINO)FERROCENYL]ETHYLDICYCLOHEXYLPHOSPHINE is known for its applications in various chemical reactions, particularly in the field of asymmetric catalysis.
Uses
Used in Homogeneous Chiral Nickel-Catalyzed Asymmetric Hydrogenation:
(R)-(-)-1-[(S)-2-(DI(3,5-DIMETHYL-4-METHOXYPHENYL)PHOSPHINO)FERROCENYL]ETHYLDICYCLOHEXYLPHOSPHINE is used as a chiral ligand in homogeneous chiral nickel-catalyzed asymmetric hydrogenation of substituted aromatic α-aminoketone hydrochlorides. This application takes advantage of the compound's ability to facilitate dynamic kinetic resolution, leading to the production of enantiomerically enriched products.
Used in Pd/Josiphos-Catalyzed Enantioselective α-Arylation:
In the field of enantioselective α-arylation, (R)-(-)-1-[(S)-2-(DI(3,5-DIMETHYL-4-METHOXYPHENYL)PHOSPHINO)FERROCENYL]ETHYLDICYCLOHEXYLPHOSPHINE serves as a crucial ligand for the Pd/Josiphos-catalyzed process. It aids in the selective arylation of silyl ketene acetals, contributing to the synthesis of chiral molecules with high enantiomeric purity.
Used in Cobalt-Catalyzed Asymmetric Addition:
(R)-(-)-1-[(S)-2-(DI(3,5-DIMETHYL-4-METHOXYPHENYL)PHOSPHINO)FERROCENYL]ETHYLDICYCLOHEXYLPHOSPHINE is also utilized as a ligand in the cobalt-catalyzed asymmetric addition of silylacetylenes to 1,1-disubstituted allenes. This application highlights the compound's versatility in promoting enantioselective reactions, leading to the formation of chiral products with potential applications in the pharmaceutical and chemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 360048-63-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,0,0,4 and 8 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 360048-63:
(8*3)+(7*6)+(6*0)+(5*0)+(4*4)+(3*8)+(2*6)+(1*3)=121
121 % 10 = 1
So 360048-63-1 is a valid CAS Registry Number.
InChI:InChI=1/C37H51O2P2.C5H5.Fe/c1-25-21-32(22-26(2)36(25)38-6)41(33-23-27(3)37(39-7)28(4)24-33)35-20-14-19-34(35)29(5)40(30-15-10-8-11-16-30)31-17-12-9-13-18-31;1-2-4-5-3-1;/h14,19-24,29-31H,8-13,15-18H2,1-7H3;1-5H;/t29-;;/m0../s1