36048-77-8

Basic information

• Product Name: (4-methoxybenzoyl)(pyridin-1-ium-1-yl)amide
• Synonyms: (4-methoxybenzoyl)(pyridin-1-ium-1-yl)amide
• CAS NO: 36048-77-8
• Molecular Weight: 228.25
• Mol File: 36048-77-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (4-methoxybenzoyl)(pyridin-1-ium-1-yl)amide(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methoxybenzoyl)(pyridin-1-ium-1-yl)amide(36048-77-8)
• EPA Substance Registry System: (4-methoxybenzoyl)(pyridin-1-ium-1-yl)amide(36048-77-8)

Safety Data

• Hazardous Substances Data: 36048-77-8(Hazardous Substances Data)

Upstream product

• 110-86-1 pyridine 
• 100-07-2 4-methoxy-benzoyl chloride 
• 25275-41-6 N-iminopyridinium ylide 
• 6295-87-0 N-aminopyridin-1-ium iodide 

Downstream Products

• 81460-57-3 N-(3,6-Dihydro-2H-pyridin-1-yl)-4-methoxy-benzamide 
• 30252-15-4 4-methoxy-N-(2-oxo-2-phenylethyl)benzamide 

Relevant articles and documents

Visible-Light-Enabled Ortho-Selective Aminopyridylation of Alkenes with N-Aminopyridinium Ylides

By utilizing an underexplored reactivity mode of N-aminopyridinium ylides, we developed the visible-light-induced ortho-selective aminopyridylation of alkenes via radical-mediated 1,3-dipolar cycloaddition. The photocatalyzed single-electron oxidation of N-aminopyridinium ylides generates the corresponding radical cations that enable previously inaccessible 1,3-cycloaddition with a broader range of alkene substrates. The resulting cycloaddition adducts rapidly undergo subsequent homolytic cleavage of the N-N bond, conferring a substantial thermodynamic driving force to yield various β-aminoethylpyridines. Remarkably, amino and pyridyl groups can be installed into both activated and unactivated alkenes with modular control of ortho-selectivity and 1,2-syn-diastereoselectivity under metal-free and mild conditions. Combined experimental and computational studies are conducted to clarify the detailed reaction mechanism and the origins of site selectivity and diastereoselectivity.

Highly regioselective synthesis of 2,4,5-(hetero)aryl substituted oxazoles by intermolecular [3+2]-cycloaddition of unsymmetrical internal alkynes

A robust N-nucleophilic 1,3-N,O-dipole equivalent reacts with unsymmetrical internal alkynes under gold catalysis. Conjugation from a remote nitrogen lone pair enables and controls this convergent and highly regioselective process.

Synthesis of N-[[(substituted-phenyl)carbonyl]amino]-1,2,3,6-tetrahydropyridines with analgesic and hyperglycemic activity

A group of N-[(phenylcarbonyl)amino]-1,2,3,6-tetrahydropyridines, 5, were synthesized to determine the effect that changes in aromatic substitution on the phenyl ring have on analgesic, hyperglycemic, and antiinflammatory activities. All of the N-[(phenyl