36051-68-0 Usage
Description
Cytidine 5'-triphosphate disodium salt, also known as CTP, is a nucleoside triphosphate with a pyrimidine ring that is present in RNA. It is a nucleotide derivative involved in phospholipid anabolism in vivo and can cross the blood-cerebrospinal fluid barrier. CTP serves as an intermediate product and energy source for cephalin synthesis and nucleic acid metabolism. It also plays a role in improving the stability and reconstruction ability of nerve cell membrane structures, supporting nerve cell survival, delaying cell aging and death, and enhancing nerve cell injury resistance and neurite outgrowth.
Uses
Used in Biochemical Reactions:
Cytidine 5'-triphosphate disodium salt is used as a pyrimidine nucleoside triphosphate salt for its involvement in various biochemical reactions, including the synthesis of RNA by RNA polymerases.
Used in Phosphatidylcholine Synthesis:
CTP is used as a reactant in the formation of phosphatidylcholine (PC), where it reacts with phosphocholine via CTP:phosphocholine cytidylyltransferases to produce CDP-choline and diphosphate. This reaction is the rate-limiting step in PC synthesis and plays a crucial role in cell proliferation, which can be significant in cancer development.
Used in Sialylation:
Cytidine 5'-triphosphate disodium salt is used as a reactant in the interaction with N-acylneuraminate, mediated by N-acylneuraminate cytidylyltransferase, to generate an intermediate required for sialylation, namely CMP-N-acylneuraminic acid.
Used in Pharmaceutical Applications:
CTP is used as a cation-permeable ligand-gated ion channel (P2X purinergic receptor) agonist and serves as an organic intermediate, pharmaceutical intermediate, food additive, and flavoring agent.
Used in the Food Industry:
Cytidine 5'-triphosphate disodium salt is used as a flavoring agent and additive in the food industry to enhance taste and improve product quality.
Chemical Properties:
Cytidine 5'-triphosphate disodium salt is a white powder with various applications in different industries, including biochemical research, pharmaceuticals, and the food industry.
Pharmacological action
Disodium cytidine triphosphate is a nucleotide derivative. It participates in phospholipid synthesis and metabolism in the body and can pass through the blood-cerebrospinal fluid barrier. It is an intermediate product and energy source between cephalin synthesis and nucleic acid metabolism, and promotes the repair of liver cells after injury , for the myocardial and brain tissue caused by vascular sclerosis, nutrition, promote regeneration and repair.
Biochem/physiol Actions
Cytidine 5′-triphosphate (CTP) prevents the action of aspartate carbamoyltransferase. This enzyme participates in pyrimidine biosynthesis. Like adenosine triphosphate (ATP), CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.
Check Digit Verification of cas no
The CAS Registry Mumber 36051-68-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,0,5 and 1 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 36051-68:
(7*3)+(6*6)+(5*0)+(4*5)+(3*1)+(2*6)+(1*8)=100
100 % 10 = 0
So 36051-68-0 is a valid CAS Registry Number.
