36078-99-6

Basic information

• Product Name: Benzoic acid, 4-(2-benzofuranyl)-, methyl ester
• CAS NO: 36078-99-6
• Molecular Formula: C16H12O3
• Molecular Weight: 252.269
• Mol File: 36078-99-6.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(2-benzofuranyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(2-benzofuranyl)-, methyl ester(36078-99-6)
• EPA Substance Registry System: Benzoic acid, 4-(2-benzofuranyl)-, methyl ester(36078-99-6)

Safety Data

• Hazardous Substances Data: 36078-99-6(Hazardous Substances Data)

Upstream product

• 271-89-6 1-benzofurane 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 696-62-8 para-iodoanisole 
• 81787-62-4 o-((trimethylsilyl)ethynyl)phenol 
• 619-44-3 methyl 4-iodobenzoate 
• 81787-63-5 2-(2-(trimethylsilyl)ethynyl)phenyl acetate 
• 67-56-1 methanol 
• 98437-24-2 benzofuran-2-boronic acid 
• 619-58-9 4-iodobenzoic acid 
• 533-58-4 2-Iodophenol 
• 3034-86-4 4-ethynylbenzoic acid methyl ester 
• 19183-08-5 4-(methoxycarbonyl)benzenediazonium chloride 
• 1416276-96-4 bis[4-(methoxycarbonyl)phenyl]iodonium trifluoromethanesulfonate 
• 74733-31-6 methyl 4-(1-(hydroxyimino)ethyl)benzoate 

Relevant articles and documents

Acid-promoted selective synthesis of trifluoromethylselenolated benzofurans with Se-(trifluoromethyl) 4-methylbenzenesulfonoselenoate

A Br?nsted acid-promoted trifluoromethylselenolation of benzofurans was disclosed by using Se-(trifluoromethyl) 4-methylbenzenesulfonoselenoate as a stable and easily prepared electrophilic trifluoromethylselenolating reagent. A wide range of SeCF3-substituted benzofuran derivatives were obtained in moderate to good yields with excellent regioselectivity. The tandem cyclization/trifluoromethylselenolation procedure of 1-methoxy-2-(arylethynyl)benzenes were also realized by engaging FeCl3 as the catalyst.

New transmetalation reagents for the gold-catalyzed visible light-enabled C(sp or sp2)-C(sp2) cross-coupling with aryldiazonium salts in the absence of a photosensitizer

The scope of photosensitizer-free visible light-driven gold-catalyzed cross-coupling was evaluated by a wide variety of organoboron and organosilicon species using four equivalents of aryldiazonium salts and (4-CF3-C6H4)3PAuCl in MeOH. In addition, a C(sp or sp2)-C(sp2) cross-coupling of organotrimethylsilanes and aryldiazonium salts was investigated. The reactions can be conducted under very mild reaction conditions, with a reduced amount of aryldiazonium salt (1.2 equiv.) by using a catalytic amount of Ph3PAuNTf2 in MeCN under irradiation with blue LEDs at room temperature.

Palladium-catalyzed phosphine-free direct C-H arylation of benzothiophenes and benzofurans involving MIDA boronates

With high regioselectivity, a series of benzoheterocyclic compounds were synthesized via palladiium-catalyzed phosphine-free C-H arylation of benzothiophenes/benzofurans with aryl MIDA boronates at 30-50 °C in moderate to excellent yields. MIDA boronates were used in C-H arylation of heterocycles for the first time. Under the optimal conditions, the benzothiophenes could be transformed into the β-arylbenzothiophenes, and the benzofurans gave only α-aryl-substituted products.