36126-89-3Relevant articles and documents
Aroyl group driven [1,2] phosphonate-phosphate/phosphine oxide-phosphinate rearrangement
Khan, Shahnawaz,Battula, Satyanarayana,Ahmed, Qazi Naveed
supporting information, p. 4273 - 4279 (2016/07/06)
Aroyl group driven phosphonate-phosphate rearrangement in dialkyl/aryl(α-hydroxy-β-oxo-β-arylethyl)phosphonates having α-proton under basic conditions is presented and extended to a novel one-pot direct coupling method between 2-oxoaldehydes (2OA) and H-p
2-Oxo promoted hydrophosphonylation & aerobic intramolecular nucleophilic displacement reaction
Battula, Satyanarayana,Battini, Narsaiah,Singh, Deepika,Ahmed, Qazi Naveed
supporting information, p. 8637 - 8641 (2015/08/24)
Highly efficient catalyst free methods for the synthesis of α-hydroxy-β-oxophosphonates and α-oxoesters have been described. The existence of a 2-oxo group in α-oxoaldehydes is a key factor in promoting the reaction of the tervalent phosphite form towards 2-oxoaldehydes in the synthesis of α-hydroxy-β-oxophosphonates. The in situ activated α-C-H atom of α-hydroxy-β-oxophosphonates sustains aerobic intramolecular nucleophilic displacement in a curious way to produce α-oxoester.
