36160-84-6

Basic information

• Product Name: 2-CHLORO-N-(4-PHENOXYPHENYL)ACETAMIDE
• Synonyms: ASISCHEM P45887;AKOS BBS-00003877;2-CHLORO-N-(4-PHENOXYPHENYL)ACETAMIDE;SALOR-INT L449814-1EA;2-Chloro-N-4-(4-phenoxyphenyl)acetamide;acetamide, 2-chloro-N-(4-phenoxyphenyl)-;2-chloro-N-[4-(phenoxy)phenyl]ethanamide
• CAS NO: 36160-84-6
• Molecular Formula: C₁₄H₁₂ClNO₂
• Molecular Weight: 261.7
• Mol File: 36160-84-6.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 439.9 °C at 760 mmHg
• Flash Point: 219.8 °C
• Appearance: /
• Density: 1.279 g/cm³
• Vapor Pressure: 6.14E-08mmHg at 25°C
• Refractive Index: 1.619
• CAS DataBase Reference: 2-CHLORO-N-(4-PHENOXYPHENYL)ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-N-(4-PHENOXYPHENYL)ACETAMIDE(36160-84-6)
• EPA Substance Registry System: 2-CHLORO-N-(4-PHENOXYPHENYL)ACETAMIDE(36160-84-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 36160-84-6(Hazardous Substances Data)

Usage

General Description

2-CHLORO-N-(4-PHENOXYPHENYL)ACETAMIDE, also known as clofibric acid, is a chemical compound used as a lipid-lowering agent and as a treatment for hyperlipidemia. It belongs to the class of fibric acid derivatives and is structurally related to the drug clofibrate. It works by increasing the breakdown of triglycerides and decreasing the production of LDL cholesterol in the liver, ultimately reducing the risk of cardiovascular diseases. However, it has been found to have potential toxic effects on the liver and kidneys in some individuals, and its use is now limited in favor of safer and more efficacious lipid-lowering agents. Due to its potential for side effects, its use as a pharmaceutical agent has declined, and it is mainly used as a research tool in studying lipid metabolism and related diseases.

InChI:InChI=1/C14H12ClNO2/c15-10-14(17)16-11-6-8-13(9-7-11)18-12-4-2-1-3-5-12/h1-9H,10H2,(H,16,17)

Upstream product

• 79-04-9 chloroacetyl chloride 
• 139-59-3 4-phenoxyanilin 

Downstream Products

• 854477-41-1 thiocyanato-acetic acid-(4-phenoxy-anilide) 
• 230309-54-3 2-(2-hydroxyethylamino)-N-(4-phenoxyphenyl)acetamide 
• 230309-51-0 2--N-(4-phenoxyphenyl)acetamide 
• 69838-05-7 N-(4-Phenoxy-phenyl)-2-piperidin-1-yl-acetamide; compound with oxalic acid 
• 854474-12-7 2-imino-3-(4-phenoxy-phenyl)-thiazolidin-4-one 
• 943785-30-6 methyl-4-[[hexahydro-4-[2-oxo-2-[(4-phenoxyphenyl)amino]ethyl]-1H-1,4-diazepin-1-yl]methyl]benzoate 
• 1160748-23-1 2-azido-N-(4-phenoxyphenyl)acetamide 
• 1360180-47-7 N-((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(3-oxobenzo[d]isothiazol-2(3H)-yl)acetamide 
• 1360180-64-8 N-(3-((1-(2-oxo-2-(4-phenoxyphenylamino)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-(3-oxobenzo[d]isothiazol-2(3H)-yl)acetamide 
• 1388657-89-3 2-(3-methoxyphenoxy)-N-(4-phenoxyphenyl)acetamide 
• 1388657-86-0 2-(3,4-difluorophenoxy)-N-(4-phenoxyphenyl)acetamide 
• 1394228-14-8 2-[(6-nitro-1H-benzimidazol-2-yl)-sulfanyl]-N-(4-phenoxyphenyl)acetamide 
• 375357-36-1 N-(4-chlorophenyl)-5-cyano-2-methyl-6-({2-oxo-2-[(4-phenoxyphenyl)-amino]ethyl}thio)-4-phenyl-1,4-dihydropyridine-3-carboxamide 

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