3618-43-7

Basic information

• Product Name: Xylenol orange tetrasodium salt
• Synonyms: Xylenol Orange, sodium salt,pure,water soluble;Tetrasodium N,N'-[3H-2,1-benzoxathiol-3-ylidenebis[(6-hydroxy-5-methylphen-3,1-ylene)methylene]]bis[N-(carboxylat;Xylenol Orange, sodiuM salt, water soluble, pure 10GR;Xylenol Orange, sodiuM salt, water soluble, pure 1GR;Xylenol Orange, sodiuM salt, water soluble, pure 5GR;Xylenol orange, sodiuM salt, ACS reagent;XYLENOL ORANGE TETRASODIUM SALT METAL IN;Xylenol Orange tetrasodiuM salt, indicator
• CAS NO: 3618-43-7
• Molecular Formula: C31H31N2Na4O13S
• Molecular Weight: 763.61
• EINECS: 222-805-8
• Mol File: 3618-43-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 195 °C (dec.)(lit.)
• Boiling Point: 904.1oC at 760 mmHg
• Flash Point: 500.6oC
• Appearance: Red/Solid
• Storage Temp.: Store at +15°C to +25°C.
• Solubility: 510g/l
• Water Solubility: 510 g/L (20 ºC)
• Stability: Stable, but may be moisture sensitive.
• CAS DataBase Reference: Xylenol orange tetrasodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: Xylenol orange tetrasodium salt(3618-43-7)
• EPA Substance Registry System: Xylenol orange tetrasodium salt(3618-43-7)

Safety Data

• Hazard Codes: Xi
• Statements: 23/24/25-36/38-36/37/38
• Safety Statements: 24/25-45-36/37-26-22-36
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 3618-43-7(Hazardous Substances Data)

Usage

Description

Xylenol Orange tetrasodium salt, also known as an acid dye or vital stain, is a red-brown to purple crystalline powder. It is widely recognized for its use as a fluorescent marker of bone growth, making it a valuable tool in the study and analysis of bone development and related conditions.

Uses

Used in Analytical Chemistry:
Xylenol Orange tetrasodium salt is used as a photometric reagent and a metal indicator for various applications in analytical chemistry. It serves as a versatile indicator for EDTA titrations in the acidic range, allowing for precise measurements and analysis of metal concentrations in different samples.
Used in Organic Reagent Applications:
As a common organic reagent, Xylenol Orange tetrasodium salt is used as an indicator for metal titrations. Its ability to change color in the presence of specific metal ions makes it a reliable and efficient tool for detecting and quantifying metal content in various industries and research settings.
Used in Biomedical Research:
In the field of biomedical research, Xylenol Orange tetrasodium salt is utilized as a fluorescent marker of bone growth. This application aids researchers in visualizing and studying the process of bone development, as well as in the identification and analysis of potential treatments for bone-related conditions and diseases.

Purification Methods

It is generally contaminated with starting material (cresol red) and semi-xylenol orange. Purify it by ion-exchange chromatography using DEAE-cellulose, eluting with 0.1M NaCl solution, which will give the sodium salt [3618-43-7] . Cresol Red, semi-xylenol orange and iminodiacetic acid bands elute first. This procedure will give the sodium salt of the dye. To obtain the free acid, dissolve the salt in H2O and acidify it with AcOH. Filter it off, wash it with H2O and dry it first in air and then in a vacuum desiccator over P2O5 in the dark [Sato et al. Anal Chim Acta 94 317 1977]. [Beilstein 19 II 111, 19 III/IV 1135, 19/3 V 461.]