36210-71-6

Basic information

• Product Name: 4-Azidobenzophenone
• Synonyms: (4-Azidophenyl)phenylmethanone;4-Azidobenzophenone
• CAS NO: 36210-71-6
• Molecular Formula: C₁₃H₉N₃O
• Molecular Weight: 0
• Mol File: 36210-71-6.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Azidobenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Azidobenzophenone(36210-71-6)
• EPA Substance Registry System: 4-Azidobenzophenone(36210-71-6)

Safety Data

• Hazardous Substances Data: 36210-71-6(Hazardous Substances Data)

Upstream product

• 1137-41-3 (4-aminophenyl)(phenyl)methanone 
• 33038-64-1 (4-Pentazol-1-yl-phenyl)-phenyl-methanone 

Downstream Products

• 1137-41-3 (4-aminophenyl)(phenyl)methanone 
• 866832-40-8 5-methyl-1-[4'-benzophenone]-1,2,3-triazole-4-carboxylic acid 
• 866832-43-1 4-amino-1-[4'-benzopheone]-5-cyano-1,2,3-triazole 
• 866832-44-2 4-amino-1-[4'-benzopheone]-5-(amidazol-2-yl)-4'',5''-dihydro-1,2,3-triazole 
• 1133862-74-4 {4-[4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]phenyl}phenylmethanone 
• 1395896-90-8 phenyl [4-(4-phenyl-1H-1,2,3-triazol-1-yl)phenyl] ketone 
• 1443134-62-0 3{1N-(4-benzoylphenyl)-1H-1,2,3-triazol-4yl}methyloxy betulinic acid 

Relevant articles and documents

Synthesis of α-santonin derived acetyl santonous acid triazole derivatives and their bioevaluation for T and B-cell proliferation

A new series of α-santonin derived acetyl santonous acid 1,2,3-triazole derivatives were synthesised using Huisgen 1,3-dipolar cyclo-addition reaction (click chemistry approach) and evaluated for their in vitro inhibition activity on concanavalin A (ConA) induced T cell proliferation and lipopolysaccharide (LPS) induced B cell proliferation. Among the synthesised series, compounds 2-10 and 19 exhibited significant inhibition against ConA and LPS stimulated T-cell and B-cell proliferation in a dose dependent manner. More significantly compounds 4, 9-10 and 19 exhibited potent inhibition activity with remarkably lower cytotoxicity on the mitogen-induced T cell and B cell proliferation at 1 μM concentration. The compound 6 displayed potent immunosuppressive effects with ～89% against LPS induced B-cell and ～83% against ConA stimulated T-cell proliferation at 100 μM concentration without cytotoxicity. Compound 10 was more selective against B cell proliferation and exhibited 81% and 69% suppression at 100 and 1 μM concentration respectively. The present study led to the identification of several santonin analogs with reduced cytotoxicity and strong inhibition activity against the cell proliferation induced by the mitogens.

Synthesis of 3-O-propargylated betulinic acid and its 1,2,3-triazoles as potential apoptotic agents

Cytotoxic agents from nature are presently the mainstay of anticancer chemotherapy, and the need to reinforce the arsenal of anticancer agents is highly desired. Chemical transformation studies carried out on betulinic acid, through concise 1,2,3-triazole

Microwave-assisted click chemistry synthesis of 1,2,3-triazoles from aryldiazonium silica sulfates in water

A microwave-assisted click chemistry synthesis of 1,4-disubstituted 1,2,3-triazoles is studied by in situ generation of aryl azides via the reaction of aryldiazonium silica sulfates and sodium azide, followed by coupling with a terminal alkyne in the presence of copper catalyst. These reactions are carried out in water under mild and heterogeneous conditions without using any additional ligands.