3625-46-5

Basic information

• Product Name: 3,7,11-trimethyldodec-1-en-3-ol
• Synonyms: 1-Dodecen-3-ol, 3,7,11-trimethyl; 1-dodecen-3-ol, 3,7,11-trimethyl-; 3,7,11-Trimethyldodec-1-en-3-ol
• CAS NO: 3625-46-5
• Molecular Formula: C₁₅H₃₀O
• Molecular Weight: 226.3981
• EINECS: 609-221-2
• Mol File: 3625-46-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 261°C at 760 mmHg
• Flash Point: 106.1°C
• Density: 0.839g/cm³
• Vapor Pressure: 0.0017mmHg at 25°C
• Refractive Index: 1.451
• CAS DataBase Reference: 3,7,11-trimethyldodec-1-en-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,7,11-trimethyldodec-1-en-3-ol(3625-46-5)
• EPA Substance Registry System: 3,7,11-trimethyldodec-1-en-3-ol(3625-46-5)

Safety Data

• Hazardous Substances Data: 3625-46-5(Hazardous Substances Data)

Upstream product

• 1604-35-9 3,7,11-trimethyldodecyn-3-ol 
• 1604-34-8 6,10-dimethyl-undecan-2-one 
• 1826-67-1 vinyl magnesium bromide 
• 67-56-1 methanol 
• 3796-70-1 trans geranyl acetone 
• 689-66-7 6,10-dimethyl-undec-5-en-2-one 
• 141-10-6 pseudoionone 
• 5392-40-5 (E/Z)-3,7-dimethyl-2,6-octadienal 
• 1604-35-9 (7R)-3,7,11-trimethyldodec-1-yn-3-ol 
• 120787-60-2 (R)-(+)-6,10-Dimethylundecan-2-one 
• 1616116-70-1 (R)-2-(2,6-dimethylheptyl)-5,5-dimethyl-1,3-dioxane 
• 60018-13-5 (+)-dihydrocitronellal 
• 1615686-25-3 (R)-6,10-dimethylundec-3-en-2-one 
• 3536-96-7 vinylmagnesium chloride 

Downstream Products

• 7278-65-1 3,7,11-trimethyldodecanol-3 
• 121239-43-8 2-(3,7,11-trimethyl-2-dodecenyl)-3,5,6-trimethyl-1,4-benzoquinone 
• 170728-14-0 6-benzyloxy-2-(4,8-dimethylnonanyl)-2,5,7-trimethylchroman 
• 170728-20-8 6-benzyloxy-8-bromo-2-(4,8-dimethylnonanyl)-2,5,7-trimethylchroman 
• 170728-24-2 6-benzyloxy-2-(4,8-dimethylnonanyl)-2,5,7-trimethylchroman-8-carboxylic acid 
• 895518-38-4 vitamin E 
• 1406-70-8 (2R,4'RS,8'RS)-α-tocopheryl acetate 
• 3891-98-3 2,6,10-trimethyldodecane 
• 110-93-0 6-Methyl-hept-5-en-2-on 
• 1313015-84-7 (5,9,13-trimethyltetradec-4-enyl) tosylate 
• 1614254-64-6 (6R,10R)-2,2-dimethoxy-6,10,14-trimethylpentadecane 
• 1614254-67-9 (6S,10R)-2,2-dimethoxy-6,10,14-trimethylpentadecane 
• 16171-35-0 2,5,7,8-tetramethyl-2-(4,8-dimethylnonyl)-6-chromanol 

Relevant articles and documents

An Efficient Alternative to the Total Synthesis of Isophytol

An improved and alternative method for the total synthesis of isophytol from citral via using pseudoionone intermediate was developed and described in this manuscript. This alternative commercially viable approach involves six steps and it represents an alternative method commercially viable over existing published synthetic methods in the literature. This goal was achieved by developing and optimizing an efficient and high yield procedure for the synthesis of a key intermediate i.e. 6,10,14-trimethylpentadectrimethylpentadec-5-en-2-one, by reacting 2-methoxypro-pene with a tertiary alcohol (3,7,11-trimethyldodec-1-ene-3-ol). Isophytol was provided in 58-60% overall yield from citral with >99% purity, evaluated by TLC, GC, and NMR.

(6R,10R)-6,10,14-TRIMETYLPENTADECAN-2-ONE PREPARED FROM 6,10-DIMETYLUNDEC-5-EN-2-ONE OR 6,10-DIMETYLUNDECA-5,9-DIEN-2-ONE

The present invention relates to a process of manufacturing (6R,10R)-6,10,14-trimetylpentadecan-2-one in a multistep synthesis from 6,10-dimetylundec-5-en-2-one or 6,10-dimetylundeca-5,9-dien-2-one. The process is very advantageous in that it forms in an efficient way the desired chiral product from a mixture of stereoisomers of the starting product.

(6R,10R)-6,10,14-TRIMETYLPENTADECAN-2-ONE PREPARED FROM 6,10-DIMETYLUNDECA-3,5,9-TRIEN-2-ONE

The present invention relates to a process of manufacturing (6R,10R) -6,10,14-trimethylpentadecan-2-one in a multistep synthesis from 6,10- dimethylundeca-3,5,9-trien-2-one. The process is very advantageous in that it forms in an efficient way the desired chiral product from a mixture of stereoisomers of the starting product.