362703-30-8

Basic information

• Product Name: methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate
• Synonyms: methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate;Methyl 4-Cyanotetrahydro-2H-Pyran-4-Carboxylate(WXC00765);methyl 4-cyanooxane-4-carboxylate
• CAS NO: 362703-30-8
• Molecular Formula: C₈H₁₁NO₃
• Molecular Weight: 169.17784
• Mol File: 362703-30-8.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate(362703-30-8)
• EPA Substance Registry System: methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate(362703-30-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 362703-30-8(Hazardous Substances Data)

Usage

General Description

Methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate is a chemical compound with the molecular formula C8H11NO3. It is a colorless liquid with a strong, fruity odor, and it is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate is a versatile building block in organic chemistry, often used in the production of various drugs and other organic compounds. It is also used in the manufacturing of perfumes, flavors, and other chemical products due to its unique properties and reactivity. methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate is an important chemical in the field of organic synthesis and is widely utilized in various industries for the production of a wide range of products.

Upstream product

• 5414-19-7 1,1'-oxybis(2-bromo-ethane) 
• 105-34-0 methyl 2-cyanoacetate 
• 111-44-4 3-oxa-1,5-dichloropentane 

Downstream Products

• 362703-32-0 4-{[4-(2-methyl-quinolin-4-ylmethoxy)-benzoylamino]-methyl}-tetrahydro-pyran-4-carboxylic acid methyl ester 
• 5337-03-1 tetrahydro-2H-pyran-4-carboxylic acid 
• 1010836-56-2 4-(hydroxymethyl)-tetrahydro-2H-pyran-4-carbonitrile 
• 1257044-40-8 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide 
• 130290-79-8 4-tetrahydropyranmethylamine 
• 1228779-96-1 3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide 
• 848821-06-7 4-cyanotetrahydro-2H-pyran-4-carboxylic acid 

Relevant articles and documents

NOVEL INHIBITOR OF CYCLIN-DEPENDENT KINASE CDK9

The present invention relates to an inhibitor of cyclin-dependent kinase CDK9, having a structure of formula (I). The present invention also provides a method of treating a cancer of a precancerous condition related to CDK9 activity with the inhibitor and a use of the same.

PROCESS FOR THE PREPARATION OF VENETOCLAX

The present disclosure provides novel synthetic process for the preparation of venetoclax. The disclosed processes involve the use of novel intermediates. Processes for the preparation of these intermediates are also disclosed as well as methods for the preparation of particularly useful salts thereof.

3-(AMINOARYL)-PYRIDINE COMPOUNDS

The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided are pharmaceutical compositions containing these compounds and methods of treating a disease or condition mediated by CDK9 using these compounds and compositions.