363162-66-7

Basic information

• Product Name: (S)-3-Methoxy-3-phenyl-propan-1-ol
• Synonyms: (S)-3-Methoxy-3-phenyl-propan-1-ol
• CAS NO: 363162-66-7
• Molecular Weight: 166.22
• Mol File: 363162-66-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-Methoxy-3-phenyl-propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-Methoxy-3-phenyl-propan-1-ol(363162-66-7)
• EPA Substance Registry System: (S)-3-Methoxy-3-phenyl-propan-1-ol(363162-66-7)

Safety Data

• Hazardous Substances Data: 363162-66-7(Hazardous Substances Data)

Upstream product

• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 153704-67-7 (S)-1-tert-butyldimethylsilyloxy-3-hydroxy-3-phenylpropane 
• 98819-68-2 3-phenyl-(2R,3R)-oxiran-2-ylmethanol 
• 96854-34-1 (S)-3-phenyl-1,3-propanediol 
• 865777-27-1 tert-butyl-(3-methoxy-3-phenyl-propoxy)-dimethyl-silane 

Downstream Products

• 865777-28-2 (S)-3-methoxy-3-phenyl-propionaldehyde 

Relevant articles and documents

Identification of potent type I MetAPs inhibitors by simple bioisosteric replacement. Part 2: SAR studies of 5-heteroalkyl substituted TCAT derivatives

Systematic SAR studies on the thiazole ring 5-substituent of TCAT derivatives revealed that the introduction of a β-alkoxy or an amino group enhanced the inhibitory activity significantly. The present compounds are representative of specific Co(II)-MetAP1 inhibitors. Before the physiologically relevant metal ions for MetAPs are established, these small molecular compounds could be used as tools for detailed biological studies.