36329-85-8 Usage
Description
3-Phenylpropylboronic Acid is an organic compound with the molecular formula C9H11BO2. It is a boronic acid derivative characterized by the presence of a phenyl group and a propyl chain attached to a boron atom. 3-PHENYLPROPYLBORONIC ACID is known for its reactivity and is commonly used in the synthesis of various organic molecules, particularly in the field of pharmaceuticals and materials science.
Uses
Used in Pharmaceutical Industry:
3-Phenylpropylboronic Acid is used as a synthetic intermediate for the production of (hetero)aryl-p-quinone derivatives. These derivatives are known for their potential therapeutic applications in treating mitochondrial diseases, which are a group of disorders caused by failures in the mitochondria, the part of the cell responsible for energy production.
In the synthesis of (hetero)aryl-p-quinone derivatives, 3-Phenylpropylboronic Acid serves as a key building block, providing the necessary structural elements for the formation of the target molecules. The resulting compounds have shown promise in addressing mitochondrial dysfunction and related health issues, making 3-Phenylpropylboronic Acid an important component in the development of novel treatments for mitochondrial diseases.
Additionally, 3-Phenylpropylboronic Acid may also find applications in other industries, such as materials science, where its reactivity and structural properties can be utilized for the development of new materials with specific properties. However, the primary use of this compound is in the pharmaceutical industry, where it plays a crucial role in the synthesis of therapeutic agents for mitochondrial diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 36329-85-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,3,2 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 36329-85:
(7*3)+(6*6)+(5*3)+(4*2)+(3*9)+(2*8)+(1*5)=128
128 % 10 = 8
So 36329-85-8 is a valid CAS Registry Number.
36329-85-8Relevant articles and documents
A General C(sp3)-C(sp3) Cross-Coupling of Benzyl Sulfonylhydrazones with Alkyl Boronic Acids
Merchant, Rohan R.,Lopez, Jovan A.
supporting information, p. 2271 - 2275 (2020/03/13)
A general transition-metal-free cross-coupling between benzylic sulfonylhydrazones and 1°, 2°, or 3° alkyl boronic acids is reported. The base-promoted reaction is operationally simple and exhibits a broad substrate scope to forge a variety of alkyl-alkyl bonds, including between sterically encumbered secondary and tertiary sp3-carbons. The ability of this method to simplify retrosynthetic analysis is exemplified by the improved synthesis of multiple medicinally relevant scaffolds.
Visible-Light-Mediated Aerobic Oxidation of Organoboron Compounds Using in Situ Generated Hydrogen Peroxide
Weng, Wei-Zhi,Liang, Hao,Zhang, Bo
supporting information, p. 4979 - 4983 (2018/08/24)
A simple and general visible-light-mediated oxidation of organoboron compounds has been developed with rose bengal as the photocatalyst, substoichiometric Et3N as the electron donor, as well as air as the oxidant. This mild and metal-free protocol shows a broad substrate scope and provides a wide range of aliphatic alcohols and phenols in moderate to excellent yields. Notably, the robustness of this method is demonstrated on the stereospecific aerobic oxidation of organoboron compounds.
Copper-promoted trifluoromethylation of primary and secondary alkylboronic acids
Xu, Jun,Xiao, Bin,Xie, Chuan-Qi,Luo, Dong-Fen,Liu, Lei,Fu, Yao
supporting information, p. 12551 - 12554 (2013/02/22)
New couple: The Cu-promoted trifluoromethylation of primary and secondary alkylboronic acids with TMSCF3 extends the scope of transition-metal-catalyzed trifluoromethylation reactions to sp 3-hybridized carbon centers. It also repres
