363590-49-2

Basic information

• Product Name: 1H-INDOLE-1-ACETIC ACID, 3-FORMYL-, 1,1-DIMETHYLETHYL ESTER
• Synonyms: 1H-INDOLE-1-ACETIC ACID, 3-FORMYL-, 1,1-DIMETHYLETHYL ESTER
• CAS NO: 363590-49-2
• Molecular Formula: C₁₅H₁₇NO₃
• Molecular Weight: 259.3
• Mol File: 363590-49-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-INDOLE-1-ACETIC ACID, 3-FORMYL-, 1,1-DIMETHYLETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-INDOLE-1-ACETIC ACID, 3-FORMYL-, 1,1-DIMETHYLETHYL ESTER(363590-49-2)
• EPA Substance Registry System: 1H-INDOLE-1-ACETIC ACID, 3-FORMYL-, 1,1-DIMETHYLETHYL ESTER(363590-49-2)

Safety Data

• Hazardous Substances Data: 363590-49-2(Hazardous Substances Data)

Usage

Type of compound

synthetic auxin (a type of plant hormone)

Use

plant growth regulator

Function

promotes growth and development of plants, enhances root formation, stimulates growth of crops, controls plant diseases, and improves yield

Industry

agricultural

Examples of use

in agricultural practices to improve plant growth and yield.

Upstream product

• 120-72-9 indole 
• 487-89-8 Indole-3-carboxaldehyde 
• 5292-43-3 bromoacetic acid tert-butyl ester 

Downstream Products

• 1374511-47-3 C₃₁H₃₁N₅O₃S 
• 1423013-88-0 4-{4-[[1-(2-tert-butoxy-2-oxoethyl)-1H-indol-3-yl]methylene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl}benzoic acid 
• 1423013-80-2 tert-butyl 2-{3-[(1-(4-chlorophenyl)-5-oxo-3-phenyl-1H-pyrazol-4(5H)-ylidene)methyl]-1H-indol-1-yl}acetate 
• 138423-98-0 3-formyl-indole-1-yl-acetic acid 
• 335207-46-0 1-[2-(4-morpholinyl)-2-oxoethyl]-1H-indole-3-carboxaldehyde 

Relevant articles and documents

Azido indol dimethine cyanine dye molecule and application

The invention discloses azido indol dimethine cyanine dye molecule and application. The azido indol dimethine cyanine dye is characterized in that indol dimethine cyanine dye is treated as a core framework; a side chain containing ester bond and azido ground is introduced into the nitrogen atom of indol. The azido indol dimethine cyanine dye has cell membrane permeability and can be applied to protein detection, vital cell staining, and determining of bacteria living state based on activity of esterase in bacteria; the amplification of dead bacteria in reaction is selectively inhibited, therefore, the purpose of quickly quantitatively detecting living bacteria can be achieved. The dye molecule has a good application prospect in the living bacteria detection.

Synthesis, crystal structure and evaluation of cancer inhibitory activity of 4-[indol-3-yl-methylene]-1H-pyrazol-5(4H)-one derivatives

A series of 4-(1H-indol-3-yl-methylene)-1H-pyrazol-5(4H)-one derivatives have been synthesised. The Z structure of 4-[(1-methyl-1H-indol-3-yl)methylene]- 3-phenyl-1-p-tolyl-1H-pyrazol-5-one was determined by X-ray crystallography. The antitumour activity was evaluated against five cancer cells by MTT assay. [(1H-Indol-3-yl)methylene]-1-(2,4-dinitrophenyl)- 3-methyl-1H-pyrazole-5-one and 4-{4-[(1-benzyl-1H-indol-3-yl)methylene]-3-methyl-5-oxo-4,5-dihydro-1Hpyrazol- 1-yl}-benzoic acid have similar anticancer activity with 5-UF on the test cancer cells (exception of A375). Almost all the target compounds displayed antitumour activity against A549 and PC-9, and those with benzyl at 1- position of indole had higher activity against PC-9 (IC50 value lower than 30 μM). Those with benzyl at the indole and carboxyl at the phenyl part of of pyrazole were more active against PC-9 and A549 cells, providing a good indication for subsequent optimisation as lung cancer inhibitory agents.