36433-88-2Relevant articles and documents
Catalysis of alkene hydrogenation and oxidation by nickel-saloph complex; a novel bifunctional catalyst
Chatterjee,Bajaj,Halligudi,Bhatt
, p. L1-L5 (1993)
Hydrogenation of cyclohexene to cyclohexane and cyclooctene to cyclooctane with H2 in presence of Ni(saloph), 1, (saloph= bis(salicylaldehyde)-o-phenylenediamine) were carried out at moderately high pressure (60 atm) and temperature (50°C) in ethanol medium. At normal temperature and pressure, the same catalyst (complex 1) catalyses the epoxidation of cyclohexene and cyclooctene with KHSO5 in presence of CTAB (cetyl trimethyl ammonium bromide; a phase-transfer reagent) in CH2Cl2. Cyclohexene oxide and cyclooctene oxide were found to be the major products of the epoxidation reactions.
Synthesis, characterization, antimicrobial, BSA binding, DFT calculation, molecular docking and cytotoxicity of Ni(II) complexes with Schiff base ligands
Rani, J. Jeevitha,Jayaseeli, A. Mary Imelda,Rajagopal,Seenithurai,Chai, Jeng-Da,Raja, J. Dhaveethu,Rajasekaran
, (2021/02/09)
A series of a tetradentate N2O2 Schiff base ligands (1a-e), [N,N′-(X)bis(salicylidene)1,2-phenylenediamine], salphens {where X = H (1a), Cl (1b), Br (1c), CH3 (1d), OCH3(1e)} were synthesized from condensation of substituted salicylaldehydes with 1,2-phenylenediamine and nickel(II) complexes(2a-e) from corresponding Schiff base ligands(1a-e). The stoichiometric ratios of the prepared ligands (1a-e) and their Ni(II)-salphen complexes (2a-e) were structurally characterized by various analytical and spectroscopic techniques such as 1H NMR, FT-IR, mass, UV‐–visible, PXRD, magnetic moments and molar conductivity measurements. These results suggest that Ni(II)-salphen complexes (2a-e) have square planar geometry. The molar conductivity measurements indicate that all complexes (2a-e) are non-electrolytes. Density Functional Theory (DFT) calculations have been used to investigate the optimized structure and chemical reactivity of these Ni(II) complexes(2a-e) from their Frontier Molecular Orbitals (FMO). The binding capabilities of the Ni(II) Schiff base complexes (2a-e) with Bovine Serum Albumin (BSA) have been studied through electronic absorption, fluorescence and cyclic voltammetric methods. Further the nature of interaction of Ni(II) complexes (2a-e) towards BSA were confirmed using molecular docking analyses. All these results demonstrated that the Ni(II) complexes 2d and 2e have better binding affinity towards BSA among all the Ni(II) complexes. The antimicrobial studies reveal that the Ni(II)-salphen complexes (2a-e) have higher inhibitory effect than ligands (1a-e) against the selected pathogenic microorganisms. Furthermore, in vitro cytotoxicity of ligands (1a-e) and Ni(II) complexes(2a-e) were evaluated by MTT assay against MCF-7. The observed IC50 values against MCF-7 cell lines suggest that Ni(II) complexes(2a-e) show more significant anticancer activity than their corresponding ligands(1a-e). It is explored that complexes 2d and 2e bearing electron donating groups have greater anticancer potency. Comparison of our results with cisplatin, Zn(II)-salphen and V(IV)-salphen complexes indicated that Ni(II)-salphen complexes can be considered as the potential candidates for use as effective anticancer agent in future.
Homogeneous photochemical water oxidation with metal salophen complexes in neutral media
Asraf, Md. Ali,Ezugwu, Chizoba I.,Zakaria,Verpoort, Francis
, p. 2782 - 2791 (2019/11/14)
The development of water oxidation catalysts based on Earth-abundant metals that can function at neutral pH remains a basic chemical challenge. Here, we report that salophen complexes with Ni(ii), Cu(ii), and Mn(ii) can catalyse photochemical water oxidat
