365-17-3

Basic information

• Product Name: 3-FLUOROBENZHYDROL
• Synonyms: 3-FLUOROBENZHYDROL
• CAS NO: 365-17-3
• Molecular Formula: C₁₃H₁₁FO
• Molecular Weight: 202.22
• Mol File: 365-17-3.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-FLUOROBENZHYDROL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-FLUOROBENZHYDROL(365-17-3)
• EPA Substance Registry System: 3-FLUOROBENZHYDROL(365-17-3)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 365-17-3(Hazardous Substances Data)

Usage

General Description

3-Fluorobenzhydrol is a chemical compound with the molecular formula C7H7FO. It is a colorless or light yellow liquid with a faint odor, and it is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. This chemical is considered to have low acute toxicity, but it may cause irritation to the skin, eyes, and respiratory tract upon exposure. It is important to handle 3-fluorobenzhydrol with caution and use appropriate personal protective equipment when working with this chemical. Additionally, proper storage and disposal procedures should be followed to minimize potential environmental and health risks.

Upstream product

• 103-73-1 Phenetole 
• 345-69-7 3-fluorobenzophenone 
• 17318-03-5 bromo(3-fluorophenyl)magnesium 
• 100-52-7 benzaldehyde 
• 1073-06-9 3-fluorobromobenzene 
• 1711-07-5 3-fluorobenzoyl chloride 
• 71-43-2 benzene 
• 1224964-61-7 3-fluorobenzhydryl tosylate 
• 1224964-64-0 3-fluorobenzhydryl mesylate 
• 108-86-1 bromobenzene 
• 456-48-4 3-Fluorobenzaldehyde 
• 13391-48-5 3-fluorobenzhydryl chloride 
• 98-80-6 phenylboronic acid 
• 768-35-4 3-fluorophenylboronic acid 

Downstream Products

• 13391-48-5 3-fluorobenzhydryl chloride 
• 365-16-2 (3-fluorophenyl)phenylbromomethane 
• 345-69-7 3-fluorobenzophenone 
• 1496-00-0 1-benzyl-3-fluorobenzene 

Relevant articles and documents

Direct C–H Carboxylation Forming Polyfunctionalized Aromatic Carboxylic Acids by Combined Br?nsted Bases

CO2 fixation into electron-deficient aromatic C–H bonds proceeds with the combined Br?nsted bases LiO-t-Bu and LiO-t-Am/CsF/18-crown-6 (t-Am = CEtMe2) under a CO2 atmosphere to afford a variety of polyfunctionalized aromat

Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase

Tryptophan (Trp) catabolizing enzymes play an important and complex role in the development of cancer. Significant evidence implicates them in a range of inflammatory and immunosuppressive activities. Whereas inhibitors of indoleamine 2,3-dioxygenase-1 (IDO1) have been reported and analyzed in the clinic, fewer inhibitors have been described for tryptophan dioxygenase (TDO) and indoleamine 2,3-dioxygenase-2 (IDO2) which also have been implicated more recently in cancer, inflammation and immune control. Consequently the development of dual or pan inhibitors of these Trp catabolizing enzymes may represent a therapeutically important area of research. This is the first report to describe the development of dual and pan inhibitors of IDO1, TDO and IDO2.

Direct electrosynthesis of ketones from benzylic methylenes by electrooxidative C-H activation

Electrify your chemistry! Direct electrosynthesis of ketones from benzylic methylenes in an undivided cell was realized in moderate to good yields (see scheme). In this electrosynthesis, electrons instead of conventional oxidants and catalysts are employed to make the reaction environmentally benign. Moreover, the reaction intermediate radical was detected by ESR spectroscopy and the reaction mechanism was clarified.