365-33-3

Basic information

• Product Name: 2-nitrobenzenediazonium tetrafluoroborate
• Synonyms: 2-nitrobenzenediazonium tetrafluoroborate;2-Nitrobenzene-1-diazonium·tetrafluoroborate;Einecs 206-673-9;o-Nitrophenyl DiazoniuM Tetrafluoroborate
• CAS NO: 365-33-3
• Molecular Formula: BF₄*C₆H₄N₃O₂
• Molecular Weight: 236.9194728
• EINECS: 206-673-9
• Mol File: 365-33-3.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 2-nitrobenzenediazonium tetrafluoroborate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-nitrobenzenediazonium tetrafluoroborate(365-33-3)
• EPA Substance Registry System: 2-nitrobenzenediazonium tetrafluoroborate(365-33-3)

Safety Data

• Hazardous Substances Data: 365-33-3(Hazardous Substances Data)

Usage

Description

2-Nitrobenzenediazonium tetrafluoroborate, with the chemical formula C6H4N2O2+ and the counterion BF4-, is an organic compound that serves as a key intermediate in various chemical reactions. It is characterized by its ability to act as a diazonium salt, which is a class of compounds known for their reactivity and versatility in organic synthesis.

Uses

Used in Organic Synthesis:
2-Nitrobenzenediazonium tetrafluoroborate is used as a synthetic intermediate for the preparation of various organic compounds. Its reactivity allows it to participate in a wide range of chemical reactions, such as coupling reactions, which are essential for the formation of new chemical bonds and the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Nitrobenzenediazonium tetrafluoroborate is utilized as a building block for the synthesis of active pharmaceutical ingredients (APIs). Its ability to form various chemical bonds makes it a valuable component in the development of new drugs with potential therapeutic applications.
Used in Dye and Pigment Industry:
2-Nitrobenzenediazonium tetrafluoroborate is also employed in the dye and pigment industry for the synthesis of azo dyes and pigments. These compounds are widely used in various applications, including textiles, plastics, and printing inks, due to their vibrant colors and stability.
Used in Chemical Research:
In the field of chemical research, 2-Nitrobenzenediazonium tetrafluoroborate serves as a valuable tool for studying reaction mechanisms and exploring new synthetic pathways. Its unique reactivity allows researchers to gain insights into the behavior of diazonium salts and their potential applications in various chemical processes.

InChI:InChI=1/C6H4N3O2.B.4FH/c7-8-5-3-1-2-4-6(5)9(10)11;;;;;/h1-4H;;4*1H/q+1;+3;;;;/p-4

Upstream product

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Relevant articles and documents

Metal-Free Visible-Light Synthesis of Arylsulfonyl Fluorides: Scope and Mechanism

The first metal-free procedure for the synthesis of arylsulfonyl fluorides is reported. Under organo-photoredox conditions, aryl diazonium salts react with a readily available SO2 source (DABSO) to afford the desired product through simple nucleophilic fluorination. The reaction tolerates the presence of both electron-rich and -poor aryls and demonstrated a broad functional group tolerance. To shed the light on the reaction mechanism, several experimental techniques were combined, including fluorescence, NMR, and EPR spectroscopy as well as DFT calculations.

Copper-mediated tandem ring-opening/cyclization reactions of cyclopropanols with aryldiazonium salts: Synthesis of: N -arylpyrazoles

A general method for the synthesis of structurally diverse N-arylpyrazoles from readily available cyclopropanols and aryldiazonium salts is disclosed. The reaction was conducted at room temperature within minutes with a broad substrate scope and excellent regioselectivity.

Method for producing 4-fluoro-3-(trifluoromethylsulfonyl)benzenesulfonamide

The invention provides a method for producing 4-fluoro-3-(trifluoromethylsulfonyl)benzenesulfonamide. 2-nitroaniline is used as an initial raw material, is subjected to diazotization reaction, trifluoromethyl sulfonation reaction, fluoronation, chlorosulfonation reaction, and is reacted with ammonium hydroxide to finally produce the 4-fluoro-3-(trifluoromethylsulfonyl)benzenesulfonamide. Comparedwith reported synthesis methods, the method for producing the 4-fluoro-3-(trifluoromethylsulfonyl)benzenesulfonamide has the advantages that the reaction yield of the synthesis route is high, used reaction agents are economic and easy to obtain, reaction conditions are mild and controllable, and in a reaction process, column chromatography and purification are not needed, so that the method for producing the 4-fluoro-3-(trifluoromethylsulfonyl)benzenesulfonamide has wide commercial application prospects.