3652-61-7

Basic information

• Product Name: ETHYL 2-METHYL-1,5-DIPHENYLPYRROLE-3-CARBOXYLATE
• Synonyms: ETHYL 2-METHYL-1,5-DIPHENYL-1H-PYRROLE-3-CARBOXYLATE;ETHYL 2-METHYL-1,5-DIPHENYLPYRROLE-3-CARBOXYLATE;2-methyl-1,5-diphenylpyrrole-3-carboxylic acid ethyl ester;ETHYL 1,5-DIPHENYL-2-METHYLPYRROLE-3-CARBOXYLATE
• CAS NO: 3652-61-7
• Molecular Formula: C₂₀H₁₉NO₂
• Molecular Weight: 305.37
• Mol File: 3652-61-7.mol
• Article Data: 13

Chemical Properties

• Melting Point: 94 °C
• Boiling Point: 459°Cat760mmHg
• Flash Point: 231.4°C
• Appearance: /
• Density: 1.08g/cm³
• Vapor Pressure: 1.31E-08mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: ETHYL 2-METHYL-1,5-DIPHENYLPYRROLE-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-METHYL-1,5-DIPHENYLPYRROLE-3-CARBOXYLATE(3652-61-7)
• EPA Substance Registry System: ETHYL 2-METHYL-1,5-DIPHENYLPYRROLE-3-CARBOXYLATE(3652-61-7)

Safety Data

• Hazardous Substances Data: 3652-61-7(Hazardous Substances Data)

Usage

General Description

ETHYL 2-METHYL-1,5-DIPHENYLPYRROLE-3-CARBOXYLATE is a chemical compound with the molecular formula C21H19NO2. It is a pyrrole derivative that consists of a pyrrole ring substituted with two phenyl groups and an ethyl ester group. ETHYL 2-METHYL-1,5-DIPHENYLPYRROLE-3-CARBOXYLATE is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active molecules. It has also been studied for its potential biological activities, including its antimicrobial and anticancer properties.ETHYL 2-METHYL-1,5-DIPHENYLPYRROLE-3-CARBOXYLATE is considered to be a valuable compound in the field of medicinal and pharmaceutical chemistry.

InChI:InChI=1/C20H19NO2/c1-3-23-20(22)18-14-19(16-10-6-4-7-11-16)21(15(18)2)17-12-8-5-9-13-17/h4-14H,3H2,1-2H3

Upstream product

• 89201-10-5 α-Phenacyl-acetessigsaeure-aethylester 
• 62-53-3 aniline 
• 109662-95-5 1-(2-amino-phenyl)-2-methyl-5-phenyl-pyrrole-3-carboxylic acid ethyl ester 
• 52313-46-9 ethyl 2-acetyl-4-oxo-4-phenylbutanoate 
• 95-54-5 1,2-diamino-benzene 
• 6287-35-0 3-phenylaminobut-2-enoic acid ethyl ester 
• 536-74-3 phenylacetylene 
• 75-52-5 nitromethane 
• 141-97-9 ethyl acetoacetate 
• 100-52-7 benzaldehyde 
• 100-42-5 styrene 
• 6287-35-0 ethyl 3-anilinocrotonate 
• 57957-24-1 N-(1-phenylvinyl)acetamide 
• 98-86-2 acetophenone 

Downstream Products

• 109812-64-8 2-methyl-1,5-diphenyl-pyrrole-3-carboxylic acid 
• 130850-61-2 4-Bromo-2-methyl-1,5-diphenyl-1H-pyrrole-3-carboxylic acid ethyl ester 
• 130850-59-8 4-Bromo-2-methyl-1,5-diphenyl-1H-pyrrole-3-carboxylic acid 

Relevant articles and documents

Novel and highly efficient preparation of pyrroles using supported ionic liquid ILCF3SO3@SiO2 as a heterogeneous catalyst

Abstract: A supported ionic liquid ILCF3SO3@SiO2 was synthesized and used as a highly efficient catalyst in the Paal–Knorr reaction for the preparation of pyrroles. The heterogeneous catalyst could be easily recovered and recycled for five times without noticeable loss of catalytic activity. Also a possible reaction mechanism is provided.

Microwave-assisted one pot synthesis of N-substitued 2-methyl-1H-pyrrole-3-carboxylate derivatives without catalyst and solvent

An efficient one-pot synthetic method for the N-substituted 2-methyl-1H-pyrrole-3-carboxylate derivatives has been accomplished via a microwave irradiation MCRs of various α-bromoacetophenone, amines, and ethyl acetoacetate without any solvent and catalys

Copper-mediated cross-coupling-cyclization-oxidation: A one-pot reaction to construct polysubstituted pyrroles

A novel and efficient procedure for the synthesis of polysubstituted pyrroles has been developed in this work. The polysubsituted pyrroles were synthesized directly from terminal alkenes, amines and β-keto esters through cross-coupling-cyclization-oxidation in the presence of a catalytic amount of cuprous chloride. This method provides a one-pot synthesis route from terminal alkenes to polysubstituted pyrroles for the first time and opens a new area in cuprous catalysis. The Royal Society of Chemistry 2014.